Vaskulær endotelial vækstfaktor-terapi ved iskæmisk hjertesygdom.

Abbas Ali Qayyum; Francis Richard Joshi; Lisbeth Drozd Lund; Rebekka Harary Søndergaard; Jens Kastrup

Vaskulær endotelial vækstfaktor-terapi ved iskæmisk hjertesygdom.

Abbas Ali Qayyum, Francis Richard Joshi, Lisbeth Drozd Lund, Rebekka Harary Søndergaard, Jens Kastrup

Afdeling for Hjertesygdomme

Abstrakt

Atherosclerosis of coronary arteries can result in a hypoxic state where myocardial cells may become dysfunctional or die. The oxygen sensing transcription factor hypoxia inducible factor 1 responds to low oxygen levels by elevating the production of angiogenic growth factors, such as vascular endothelial growth factor (VEGF). Despite this, endogenous processes and conventional therapies are inefficient in some patients. To stimulate angiogenesis, VEGF has been injected into the myocardium. As stated in this review, this therapy has so far been proven safe and studies are conducted in several countries, including Denmark.

Bidragets oversatte titel	Vascular endothelial growth factor therapy in ischaemic heart disease
Originalsprog	Dansk
Tidsskrift	Ugeskrift for Laeger
Vol/bind	182
Udgave nummer	44
ISSN	0041-5782
Status	Udgivet - 26 okt. 2020

Citationsformater

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title = "Vaskul{\ae}r endotelial v{\ae}kstfaktor-terapi ved isk{\ae}misk hjertesygdom.",

abstract = "Atherosclerosis of coronary arteries can result in a hypoxic state where myocardial cells may become dysfunctional or die. The oxygen sensing transcription factor hypoxia inducible factor 1 responds to low oxygen levels by elevating the production of angiogenic growth factors, such as vascular endothelial growth factor (VEGF). Despite this, endogenous processes and conventional therapies are inefficient in some patients. To stimulate angiogenesis, VEGF has been injected into the myocardium. As stated in this review, this therapy has so far been proven safe and studies are conducted in several countries, including Denmark.",

author = "Qayyum, {Abbas Ali} and Joshi, {Francis Richard} and Lund, {Lisbeth Drozd} and S{\o}ndergaard, {Rebekka Harary} and Jens Kastrup",

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month = oct,

day = "26",

language = "Dansk",

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journal = "Ugeskrift for Laeger",

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TY - JOUR

T1 - Vaskulær endotelial vækstfaktor-terapi ved iskæmisk hjertesygdom.

AU - Qayyum, Abbas Ali

AU - Joshi, Francis Richard

AU - Lund, Lisbeth Drozd

AU - Søndergaard, Rebekka Harary

AU - Kastrup, Jens

PY - 2020/10/26

Y1 - 2020/10/26

N2 - Atherosclerosis of coronary arteries can result in a hypoxic state where myocardial cells may become dysfunctional or die. The oxygen sensing transcription factor hypoxia inducible factor 1 responds to low oxygen levels by elevating the production of angiogenic growth factors, such as vascular endothelial growth factor (VEGF). Despite this, endogenous processes and conventional therapies are inefficient in some patients. To stimulate angiogenesis, VEGF has been injected into the myocardium. As stated in this review, this therapy has so far been proven safe and studies are conducted in several countries, including Denmark.

AB - Atherosclerosis of coronary arteries can result in a hypoxic state where myocardial cells may become dysfunctional or die. The oxygen sensing transcription factor hypoxia inducible factor 1 responds to low oxygen levels by elevating the production of angiogenic growth factors, such as vascular endothelial growth factor (VEGF). Despite this, endogenous processes and conventional therapies are inefficient in some patients. To stimulate angiogenesis, VEGF has been injected into the myocardium. As stated in this review, this therapy has so far been proven safe and studies are conducted in several countries, including Denmark.

M3 - Tidsskriftartikel

C2 - 33118488

VL - 182

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

SN - 0041-5782

IS - 44

ER -

Vaskulær endotelial vækstfaktor-terapi ved iskæmisk hjertesygdom.

Abstrakt

Fingeraftryk

Citationsformater