TY - JOUR
T1 - Variations in reporting of outcomes in randomized trials on diet and physical activity in pregnancy
T2 - A systematic review
AU - Rogozińska, Ewelina
AU - Marlin, Nadine
AU - Yang, Fen
AU - Dodd, Jodie M
AU - Guelfi, Kym
AU - Teede, Helena
AU - Surita, Fernanda
AU - Jensen, Dorte Møller
AU - Geiker, Nina R W
AU - Astrup, Arne
AU - Yeo, SeonAe
AU - Kinnunen, Tarja I
AU - Stafne, Signe Nilssen
AU - Cecatti, Jose Guilherme
AU - Bogaerts, Annick
AU - Hauner, Hans
AU - Mol, Ben Willem J
AU - Scudeller, Tânia T
AU - Vinter, Christina Anne
AU - Renault, Kristina M
AU - Devlieger, Roland
AU - Thangaratinam, Shakila
AU - Khan, Khalid S
AU - i-WIP (International Weight Management in Pregnancy) Collaborative Group
N1 - © 2017 Japan Society of Obstetrics and Gynecology.
PY - 2017/7/1
Y1 - 2017/7/1
N2 - AIM: Trials on diet and physical activity in pregnancy report on various outcomes. We aimed to assess the variations in outcomes reported and their quality in trials on lifestyle interventions in pregnancy.METHODS: We searched major databases without language restrictions for randomized controlled trials on diet and physical activity-based interventions in pregnancy up to March 2015. Two independent reviewers undertook study selection and data extraction. We estimated the percentage of papers reporting 'critically important' and 'important' outcomes. We defined the quality of reporting as a proportion using a six-item questionnaire. Regression analysis was used to identify factors affecting this quality.RESULTS: Sixty-six randomized controlled trials were published in 78 papers (66 main, 12 secondary). Gestational diabetes (57.6%, 38/66), preterm birth (48.5%, 32/66) and cesarian section (60.6%, 40/66), were the commonly reported 'critically important' outcomes. Gestational weight gain (84.5%, 56/66) and birth weight (87.9%, 58/66) were reported in most papers, although not considered critically important. The median quality of reporting was 0.60 (interquartile range 0.25, 0.83) for a maximum score of one. Study and journal characteristics did not affect quality.CONCLUSION: Many studies on lifestyle interventions in pregnancy do not report critically important outcomes, highlighting the need for core outcome set development.
AB - AIM: Trials on diet and physical activity in pregnancy report on various outcomes. We aimed to assess the variations in outcomes reported and their quality in trials on lifestyle interventions in pregnancy.METHODS: We searched major databases without language restrictions for randomized controlled trials on diet and physical activity-based interventions in pregnancy up to March 2015. Two independent reviewers undertook study selection and data extraction. We estimated the percentage of papers reporting 'critically important' and 'important' outcomes. We defined the quality of reporting as a proportion using a six-item questionnaire. Regression analysis was used to identify factors affecting this quality.RESULTS: Sixty-six randomized controlled trials were published in 78 papers (66 main, 12 secondary). Gestational diabetes (57.6%, 38/66), preterm birth (48.5%, 32/66) and cesarian section (60.6%, 40/66), were the commonly reported 'critically important' outcomes. Gestational weight gain (84.5%, 56/66) and birth weight (87.9%, 58/66) were reported in most papers, although not considered critically important. The median quality of reporting was 0.60 (interquartile range 0.25, 0.83) for a maximum score of one. Study and journal characteristics did not affect quality.CONCLUSION: Many studies on lifestyle interventions in pregnancy do not report critically important outcomes, highlighting the need for core outcome set development.
KW - Journal Article
U2 - 10.1111/jog.13338
DO - 10.1111/jog.13338
M3 - Review
C2 - 28613023
SN - 1341-8076
VL - 43
SP - 1101
EP - 1110
JO - Journal of Obstetrics and Gynaecology Research
JF - Journal of Obstetrics and Gynaecology Research
IS - 7
ER -