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Validity and reliability of the Thai version of the thyroid-related patient-reported outcome — A thyroid-specific quality of life questionnaire

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review


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  • Patorn Piromchai
  • Supachat Chaiudomsom
  • Pattaramon Wijakkanalan
  • Torquil Watt
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Introduction The Thyroid-Related Patient-Reported Outcome (ThyPRO) is a new thyroid-specific quality of life patient-reported outcome measure for benign thyroid disorders. Objective The objective of this study was to investigate the face validity, internal consistency, and test-retest reliability of the Thai version of the ThyPRO (ThyPROth). Methods The translation of the ThyPRO questionnaire was performed using double forward translation, reconciliation, single backward translation, and cognitive debriefing, followed by a panel review. Five thyroid patients evaluated the face validity. The internal consistency and test-retest reliability were evaluated in 30 patients with thyroid diseases. Results The overall validity score was 3.75 (range 0–4). The Cronbach α coefficient ranged from 0.76 to 0.95, with a total coefficient of 0.97 (95% CI 0.962–0.959), indicating excellent internal consistency. The test-retest reliability coefficient ranged from 0.70 to 0.97. All values were 0.70 and above. The total reliability coefficient was 0.86 (95% CI 0.724–0.932), indicating excellent reliability. Conclusion The ThyPROth was found to be valid and to exhibit good internal consistency and test-retest reliability. The questionnaire is ready for implementation in the assessment of health-related quality of life in Thai patients with benign thyroid diseases.

TidsskriftInternational Archives of Otorhinolaryngology
Udgave nummer1
Sider (fra-til)92-97
Antal sider6
StatusUdgivet - jan. 2021

Bibliografisk note

Funding Information:
The authors would like to thank the patients for their participation in the study and the staff at Srinagarind Hospital for their assistance. We would also like to thank Dr Dylan Southard (D.S.) for backwards translation of the questionnaire and for editting this manuscript, and Duncan Mark Foster (D.F.) for comparing the Thai version of the ThyPROth with the original version. Faculty of Medicine, Khon Kaen University for internal (grant number: IN61141 and AS62102).

Publisher Copyright:
© 2020. Fundação Otorrinolaringologia. All rights reserved.

Copyright 2021 Elsevier B.V., All rights reserved.

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