TY - JOUR
T1 - Validation of the Endoscopic Part of the Spigelman Classification for Evaluating Duodenal Adenomatosis in Familial Adenomatous Polyposis
T2 - A Prospective Study of Interrater and Intrarater Reliability
AU - Karstensen, John Gásdal
AU - Bülow, Steffen
AU - Burisch, Johan
AU - Ellebæk, Mark Bremholm
AU - Ostapiuk, Marcin
AU - Pommergaard, Hans Christian
AU - Schmidt, Palle Nordblad
N1 - Copyright © 2021 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of The American College of Gastroenterology.
PY - 2022/2
Y1 - 2022/2
N2 - INTRODUCTION: In patients with familial adenomatous polyposis, the Spigelman classification is recommended for staging and risk stratification of duodenal adenomatosis. Although the classification has been used for decades, it has never been formally validated.METHODS: We included consecutive FAP patients undergoing upper gastrointestinal endoscopic surveillance and evaluated the inter- and intrarater reliability of the Spigelman classification.RESULTS: The interrater reliability of the endoscopic parameters and the Spigelman classification was good and excellent, respectively. The intrarater reliability of the endoscopic parameters and the Spigelman classification was moderate and good, respectively.DISCUSSION: The results support continued use of the Spigelman classification as the primary end point for future studies and as key endoscopic performance measure.
AB - INTRODUCTION: In patients with familial adenomatous polyposis, the Spigelman classification is recommended for staging and risk stratification of duodenal adenomatosis. Although the classification has been used for decades, it has never been formally validated.METHODS: We included consecutive FAP patients undergoing upper gastrointestinal endoscopic surveillance and evaluated the inter- and intrarater reliability of the Spigelman classification.RESULTS: The interrater reliability of the endoscopic parameters and the Spigelman classification was good and excellent, respectively. The intrarater reliability of the endoscopic parameters and the Spigelman classification was moderate and good, respectively.DISCUSSION: The results support continued use of the Spigelman classification as the primary end point for future studies and as key endoscopic performance measure.
KW - Adenomatous Polyposis Coli/classification
KW - Adult
KW - Biopsy
KW - Duodenal Neoplasms/classification
KW - Duodenoscopy/methods
KW - Duodenum/pathology
KW - Female
KW - Follow-Up Studies
KW - Humans
KW - Male
KW - Neoplasm Staging/methods
KW - Prospective Studies
KW - ROC Curve
KW - Reproducibility of Results
UR - http://www.scopus.com/inward/record.url?scp=85124056501&partnerID=8YFLogxK
U2 - 10.14309/ajg.0000000000001582
DO - 10.14309/ajg.0000000000001582
M3 - Journal article
C2 - 34913876
SN - 0002-9270
VL - 117
SP - 343
EP - 345
JO - The American journal of gastroenterology
JF - The American journal of gastroenterology
IS - 2
M1 - 0000000000001582
ER -