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Udgivet

Validating Optos® ultra wide-field imaging against conventional Topcon® imaging

Publikation: Bidrag til tidsskriftKonferenceabstrakt i tidsskriftForskningpeer review

  1. Evaluation of a screening algorithm for detection of diabetic retinopathy based on quantitation of retinal pathological elements

    Publikation: Bidrag til tidsskriftKonferenceabstrakt i tidsskriftForskningpeer review

  1. Melanopsin-mediated pupillary light reflex and sleep quality in patients with normal tension glaucoma

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Habitual activity associates with lower fasting and greater glucose-induced GLP-1 response in men

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Optos wide-field imaging versus conventional camera imaging in Danish patients with type 2 diabetes

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  4. Fat- and fat-free mass growth in infancy in relation to cardiometabolic risk profile and body composition at 5 years of age – the IABC study

    Publikation: KonferencebidragKonferenceabstrakt til konferenceForskningpeer review

Vis graf over relationer
Purpose: Current diabetic retinopathy screening methods are costly, require highly specialized personnel and patient mydriasis. The new Optos® apparatus can be operated by non-specialists and provides ultra wide-field imaging, with 200° views of the retina in a single image. Conventional methods only provide 90° image views of the retina in up to 16 images. We aimed to validate the Optos® imaging against conventional Topcon® imaging for grading retinopathy. Methods: We conducted a follow-up study of 101 persons with diabetes who participated in the Addition-DK study. Retina fundus photos using both Optos® and Topcon® imaging were taken for both eyes among all participants. All photos were graded by specialist ophthalmologic nurses, using an adaptation of the Early Treatment Diabetic Retinopathy Scale (ETDRS). We constructed frequency tables separately for peripheral- and macular grading. Levels of agreement between the grading of Optos® and Topcon® images were assessed using weighted Kappa statistics, separately for peripheral and macular imaging. Results: Using Optos® imaging, a larger proportion of the peripheral grading was determined “grade 1” or “grade 2”compared with Topcon® (Figure 1). The inter-camera agreement was substantial (0.63 (95%CI: 0.39-0.87)) for macular retinopathy and fair (0.30 (95%CI: 0.16-0.44)) for peripheral retinopathy (both with a P-value<0.001). Conclusions: The inter-camera agreement was acceptable for macular retinopathy, but only fair for peripheral retinopathy, with the Optos® apparatus finding more microvascular changes in the periphery than the conventional Topcon® apparatus. Whether this has any clinical significance remains to be explored.
OriginalsprogEngelsk
TidsskriftInvestigative Ophthalmology & Visual Science
Vol/bind59
Udgave nummer9
ISSN0146-0404
StatusUdgivet - 1 maj 2018
BegivenhedARVO - Honolulu, Hawaii, USA
Varighed: 29 apr. 20183 maj 2018

Konference

KonferenceARVO
LokationHonolulu, Hawaii
LandUSA
Periode29/04/201803/05/2018

Begivenhed

ARVO

29/04/201803/05/2018

USA

Begivenhed: Konference

ID: 55857233