Vaccination mod herpes zoster

Carsten Schade Larsen, Marie Helleberg

Abstract

During their lifetime, 25% of Danes will experience an episode of herpes zoster (HZ). In 15-20% of these 25% HZ will be complicated by postherpetic neuralgia (PHN). The European Medicines Agency has approved two vaccines against HZ, a live attenuated vaccine (ZLV) and a recombinant adjuvanted vaccine (RZV). The efficacy of ZLV against HZ is moderate (51%), age-dependent and declines in 5-8 years. RZV has shown greater-than 90% protection against HZ and PHN across age groups for ≥ 9 years as summarised in this review. Vaccination of everybody > 50 years of age and immunocompromised patients > 18 years of age against HZ with RZV is recommend in several countries and should also be considered in Denmark.

Bidragets oversatte titelVaccination against herpes zoster
OriginalsprogDansk
TidsskriftUgeskrift for Laeger
Vol/bind183
Udgave nummer47
ISSN0041-5782
StatusUdgivet - 22 nov. 2021

Emneord

  • Child
  • Child, Preschool
  • Herpes Zoster Vaccine
  • Herpes Zoster/prevention & control
  • Herpesvirus 3, Human
  • Humans
  • Neuralgia, Postherpetic/prevention & control
  • Vaccination

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