Using genetic loci to understand the relationship between adiposity and psychological distress: a Mendelian Randomization study in the Copenhagen General Population Study of 53,221 adults

Debbie A Lawlor; Roger M Harbord; Anne  Tybjærg-Hansen; Tom M Palmer; Jeppe Zacho; Marianne Benn; Nicholas J Timpson; George Davey Smith; Børge G Nordestgaard

doi:10.1111/j.1365-2796.2011.02343.x

Using genetic loci to understand the relationship between adiposity and psychological distress: a Mendelian Randomization study in the Copenhagen General Population Study of 53,221 adults

Debbie A Lawlor
, Roger M Harbord
, Anne Tybjærg-Hansen
, Tom M Palmer
, Jeppe Zacho
, Marianne Benn
, Nicholas J Timpson
, George Davey Smith
, Børge G Nordestgaard

Afdeling for Klinisk Biokemi DIA

60 Citationer (Scopus)

Abstract

We used genetic variants that are robustly associated with adiposity to examine the causal association of adiposity with psychological distress.

Originalsprog	Engelsk
Tidsskrift	Journal of Internal Medicine
Vol/bind	269
Udgave nummer	5
Sider (fra-til)	525-37
Antal sider	13
ISSN	0954-6820
DOI	https://doi.org/10.1111/j.1365-2796.2011.02343.x
Status	Udgivet - 2011

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10.1111/j.1365-2796.2011.02343.x

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Lawlor, D. A., Harbord, R. M., Tybjærg-Hansen, A., Palmer, T. M., Zacho, J., Benn, M., Timpson, N. J., Smith, G. D., & Nordestgaard, B. G. (2011). Using genetic loci to understand the relationship between adiposity and psychological distress: a Mendelian Randomization study in the Copenhagen General Population Study of 53,221 adults. Journal of Internal Medicine, 269(5), 525-37. https://doi.org/10.1111/j.1365-2796.2011.02343.x

Using genetic loci to understand the relationship between adiposity and psychological distress: a Mendelian Randomization study in the Copenhagen General Population Study of 53,221 adults. / Lawlor, Debbie A; Harbord, Roger M; Tybjærg-Hansen, Anne et al.
I: Journal of Internal Medicine, Bind 269, Nr. 5, 2011, s. 525-37.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

Lawlor, DA, Harbord, RM, Tybjærg-Hansen, A, Palmer, TM, Zacho, J, Benn, M, Timpson, NJ, Smith, GD & Nordestgaard, BG 2011, 'Using genetic loci to understand the relationship between adiposity and psychological distress: a Mendelian Randomization study in the Copenhagen General Population Study of 53,221 adults', Journal of Internal Medicine, bind 269, nr. 5, s. 525-37. https://doi.org/10.1111/j.1365-2796.2011.02343.x

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abstract = "We used genetic variants that are robustly associated with adiposity to examine the causal association of adiposity with psychological distress.",

keywords = "Adiposity, Adult, Aged, Aged, 80 and over, Anxiety Disorders, Body Mass Index, Cohort Studies, Cross-Sectional Studies, Denmark, Female, Genetic Loci, Genotype, Humans, Male, Mendelian Randomization Analysis, Middle Aged, Proteins, Receptor, Melanocortin, Type 4, Risk Factors, Stress, Psychological, Waist-Hip Ratio, Young Adult",

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AU - Lawlor, Debbie A

AU - Harbord, Roger M

AU - Tybjærg-Hansen, Anne

AU - Palmer, Tom M

AU - Zacho, Jeppe

AU - Benn, Marianne

AU - Timpson, Nicholas J

AU - Smith, George Davey

AU - Nordestgaard, Børge G

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KW - Aged, 80 and over

KW - Anxiety Disorders

KW - Body Mass Index

KW - Cohort Studies

KW - Cross-Sectional Studies

KW - Denmark

KW - Female

KW - Genetic Loci

KW - Genotype

KW - Humans

KW - Male

KW - Mendelian Randomization Analysis

KW - Middle Aged

KW - Proteins

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KW - Stress, Psychological

KW - Waist-Hip Ratio

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Using genetic loci to understand the relationship between adiposity and psychological distress: a Mendelian Randomization study in the Copenhagen General Population Study of 53,221 adults

Abstract

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