TY - JOUR
T1 - Urinary Tract Infection in Children and the Potential Role of Pivmecillinam as a Treatment Option
AU - Andersen, Naja Lyhne
AU - Antsupova, Valeria
AU - Boel, Jonas Bredtoft
AU - Christensen, Mette Marie
AU - Nygaard, Ulrikka
AU - Schmidt, Lisbeth Samsø
N1 - Publisher Copyright:
Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.
PY - 2025/1
Y1 - 2025/1
N2 - We investigated the potential role of pivmecillinam in the treatment of urinary tract infections in children. Among 351 children (0–6 years) with urinary tract infections, 83% could be treated with pivmecillinam following urine culture. Resistance was highest in infants (0–3 months) caused by the high prevalence of Enterococcus faecalis. This result emphasizes the necessity for developing a pediatric oral form of pivmecillinam.
AB - We investigated the potential role of pivmecillinam in the treatment of urinary tract infections in children. Among 351 children (0–6 years) with urinary tract infections, 83% could be treated with pivmecillinam following urine culture. Resistance was highest in infants (0–3 months) caused by the high prevalence of Enterococcus faecalis. This result emphasizes the necessity for developing a pediatric oral form of pivmecillinam.
KW - antimicrobial resistance
KW - children
KW - Gram-negative bacteria
KW - pivmecillinam
KW - urinary tract infection
UR - http://www.scopus.com/inward/record.url?scp=85203130966&partnerID=8YFLogxK
U2 - 10.1097/INF.0000000000004524
DO - 10.1097/INF.0000000000004524
M3 - Journal article
C2 - 39705404
AN - SCOPUS:85203130966
SN - 0891-3668
VL - 44
SP - e1-e3
JO - Pediatric Infectious Disease Journal
JF - Pediatric Infectious Disease Journal
IS - 1
ER -