Uptake of the OMERACT-OARSI Hip and Knee Osteoarthritis Core Outcome Set: Review of Randomized Controlled Trials from 1997 to 2017

Toby O Smith; Michael Mansfield; Gillian A Hawker; David J Hunter; Lyn M March; Maarten Boers; Beverley J Shea; Robin Christensen; Francis Guillemin; Caroline B Terwee; Paula R Williamson; Ewa M Roos; Richard F Loeser; Thomas J Schnitzer; Margreet Kloppenburg; Tuhina Neogi; Christoph H Ladel; Gurdyal Kalsi; Ulrike Kaiser; Thomas W Buttel; Anne E Ashford; Ali Mobasheri; Nigel K Arden; Alan Tennant; Marc C Hochberg; Maarten de Wit; Peter Tugwell; Philip G Conaghan

doi:10.3899/jrheum.181066

Uptake of the OMERACT-OARSI Hip and Knee Osteoarthritis Core Outcome Set: Review of Randomized Controlled Trials from 1997 to 2017

Toby O Smith, Michael Mansfield, Gillian A Hawker, David J Hunter, Lyn M March, Maarten Boers, Beverley J Shea, Robin Christensen, Francis Guillemin, Caroline B Terwee, Paula R Williamson, Ewa M Roos, Richard F Loeser, Thomas J Schnitzer, Margreet Kloppenburg, Tuhina Neogi, Christoph H Ladel, Gurdyal Kalsi, Ulrike Kaiser, Thomas W ButtelAnne E Ashford, Ali Mobasheri, Nigel K Arden, Alan Tennant, Marc C Hochberg, Maarten de Wit, Peter Tugwell, Philip G Conaghan

Parker Instituttet

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Abstract

OBJECTIVE: To assess the uptake of the OMERACT-OARSI (Outcome Measures in Rheumatology- Osteoarthritis Research Society International) core outcome set (COS) domains in hip and/or knee osteoarthritis (OA) trials.

METHODS: There were 382 trials of hip and/or knee OA identified from the ClinicalTrial.gov registry from 1997 to 2017. Frequency of COS adoption was assessed by year and per 5-yearly phases.

RESULTS: COS adoption decreased from 61% between 1997 and 2001 to 38% between 2012 and 2016. Pain (95%) and physical function (86%) were most consistently adopted. Patient's global assessment (48%) was the principal missing domain.

CONCLUSION: Limited adoption of the COS domains indicates that further consideration to improve uptake is required.

Originalsprog	Engelsk
Tidsskrift	Journal of Rheumatology
Vol/bind	46
Udgave nummer	8
Sider (fra-til)	976-980
Antal sider	5
ISSN	0315-162X
DOI	https://doi.org/10.3899/jrheum.181066
Status	Udgivet - aug. 2019

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Smith, T. O., Mansfield, M., Hawker, G. A., Hunter, D. J., March, L. M., Boers, M., Shea, B. J., Christensen, R., Guillemin, F., Terwee, C. B., Williamson, P. R., Roos, E. M., Loeser, R. F., Schnitzer, T. J., Kloppenburg, M., Neogi, T., Ladel, C. H., Kalsi, G., Kaiser, U., ... Conaghan, P. G. (2019). Uptake of the OMERACT-OARSI Hip and Knee Osteoarthritis Core Outcome Set: Review of Randomized Controlled Trials from 1997 to 2017. Journal of Rheumatology, 46(8), 976-980. https://doi.org/10.3899/jrheum.181066

Smith, TO, Mansfield, M, Hawker, GA, Hunter, DJ, March, LM, Boers, M, Shea, BJ, Christensen, R, Guillemin, F, Terwee, CB, Williamson, PR, Roos, EM, Loeser, RF, Schnitzer, TJ, Kloppenburg, M, Neogi, T, Ladel, CH, Kalsi, G, Kaiser, U, Buttel, TW, Ashford, AE, Mobasheri, A, Arden, NK, Tennant, A, Hochberg, MC, de Wit, M, Tugwell, P & Conaghan, PG 2019, 'Uptake of the OMERACT-OARSI Hip and Knee Osteoarthritis Core Outcome Set: Review of Randomized Controlled Trials from 1997 to 2017', Journal of Rheumatology, bind 46, nr. 8, s. 976-980. https://doi.org/10.3899/jrheum.181066

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abstract = "OBJECTIVE: To assess the uptake of the OMERACT-OARSI (Outcome Measures in Rheumatology- Osteoarthritis Research Society International) core outcome set (COS) domains in hip and/or knee osteoarthritis (OA) trials.METHODS: There were 382 trials of hip and/or knee OA identified from the ClinicalTrial.gov registry from 1997 to 2017. Frequency of COS adoption was assessed by year and per 5-yearly phases.RESULTS: COS adoption decreased from 61% between 1997 and 2001 to 38% between 2012 and 2016. Pain (95%) and physical function (86%) were most consistently adopted. Patient's global assessment (48%) was the principal missing domain.CONCLUSION: Limited adoption of the COS domains indicates that further consideration to improve uptake is required.",

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pages = "976--980",

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AU - Smith, Toby O

AU - Mansfield, Michael

AU - Hawker, Gillian A

AU - Hunter, David J

AU - March, Lyn M

AU - Boers, Maarten

AU - Shea, Beverley J

AU - Christensen, Robin

AU - Guillemin, Francis

AU - Terwee, Caroline B

AU - Williamson, Paula R

AU - Roos, Ewa M

AU - Loeser, Richard F

AU - Schnitzer, Thomas J

AU - Kloppenburg, Margreet

AU - Neogi, Tuhina

AU - Ladel, Christoph H

AU - Kalsi, Gurdyal

AU - Kaiser, Ulrike

AU - Buttel, Thomas W

AU - Ashford, Anne E

AU - Mobasheri, Ali

AU - Arden, Nigel K

AU - Tennant, Alan

AU - Hochberg, Marc C

AU - de Wit, Maarten

AU - Tugwell, Peter

AU - Conaghan, Philip G

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Uptake of the OMERACT-OARSI Hip and Knee Osteoarthritis Core Outcome Set: Review of Randomized Controlled Trials from 1997 to 2017

Abstract

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