Uptake of the OMERACT-OARSI Hip and Knee Osteoarthritis Core Outcome Set: Review of Randomized Controlled Trials from 1997 to 2017

Toby O Smith, Michael Mansfield, Gillian A Hawker, David J Hunter, Lyn M March, Maarten Boers, Beverley J Shea, Robin Christensen, Francis Guillemin, Caroline B Terwee, Paula R Williamson, Ewa M Roos, Richard F Loeser, Thomas J Schnitzer, Margreet Kloppenburg, Tuhina Neogi, Christoph H Ladel, Gurdyal Kalsi, Ulrike Kaiser, Thomas W ButtelAnne E Ashford, Ali Mobasheri, Nigel K Arden, Alan Tennant, Marc C Hochberg, Maarten de Wit, Peter Tugwell, Philip G Conaghan

24 Citationer (Scopus)

Abstract

OBJECTIVE: To assess the uptake of the OMERACT-OARSI (Outcome Measures in Rheumatology- Osteoarthritis Research Society International) core outcome set (COS) domains in hip and/or knee osteoarthritis (OA) trials.

METHODS: There were 382 trials of hip and/or knee OA identified from the ClinicalTrial.gov registry from 1997 to 2017. Frequency of COS adoption was assessed by year and per 5-yearly phases.

RESULTS: COS adoption decreased from 61% between 1997 and 2001 to 38% between 2012 and 2016. Pain (95%) and physical function (86%) were most consistently adopted. Patient's global assessment (48%) was the principal missing domain.

CONCLUSION: Limited adoption of the COS domains indicates that further consideration to improve uptake is required.

OriginalsprogEngelsk
TidsskriftJournal of Rheumatology
Vol/bind46
Udgave nummer8
Sider (fra-til)976-980
Antal sider5
ISSN0315-162X
DOI
StatusUdgivet - aug. 2019

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