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Updating the Psoriatic Arthritis (PsA) Core Domain Set: A Report from the PsA Workshop at OMERACT 2016

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

DOI

  1. Adaptive Trial Designs in Rheumatology: Report from the OMERACT Special Interest Group

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. OMERACT Definitions for Ultrasonographic Pathologies and Elementary Lesions of Rheumatic Disorders 15 Years On

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. OMERACT Development of a Core Domain Set of Outcomes for Shared Decision-making Interventions

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. Adaptive Trial Designs in Rheumatology: Report from the OMERACT Special Interest Group

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. OMERACT Development of a Core Domain Set of Outcomes for Shared Decision-making Interventions

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  • Ana-Maria Orbai
  • Maarten de Wit
  • Philip J Mease
  • Kristina Callis Duffin
  • Musaab Elmamoun
  • William Tillett
  • Willemina Campbell
  • Oliver FitzGerald
  • Dafna D Gladman
  • Niti Goel
  • Laure Gossec
  • Pil Hoejgaard
  • Ying Ying Leung
  • Chris Lindsay
  • Vibeke Strand
  • Désirée M van der Heijde
  • Bev Shea
  • Robin Christensen
  • Laura Coates
  • Lihi Eder
  • Neil McHugh
  • Umut Kalyoncu
  • Ingrid Steinkoenig
  • Alexis Ogdie
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OBJECTIVE: To include the patient perspective in accordance with the Outcome Measures in Rheumatology (OMERACT) Filter 2.0 in the updated Psoriatic Arthritis (PsA) Core Domain Set for randomized controlled trials (RCT) and longitudinal observational studies (LOS).

METHODS: At OMERACT 2016, research conducted to update the PsA Core Domain Set was presented and discussed in breakout groups. The updated PsA Core Domain Set was voted on and endorsed by OMERACT participants.

RESULTS: We conducted a systematic literature review of domains measured in PsA RCT and LOS, and identified 24 domains. We conducted 24 focus groups with 130 patients from 7 countries representing 5 continents to identify patient domains. We achieved consensus through 2 rounds of separate surveys with 50 patients and 75 physicians, and a nominal group technique meeting with 12 patients and 12 physicians. We conducted a workshop and breakout groups at OMERACT 2016 in which findings were presented and discussed. The updated PsA Core Domain Set endorsed with 90% agreement by OMERACT 2016 participants included musculoskeletal disease activity, skin disease activity, fatigue, pain, patient's global assessment, physical function, health-related quality of life, and systemic inflammation, which were recommended for all RCT and LOS. These were important, but not required in all RCT and LOS: economic cost, emotional well-being, participation, and structural damage. Independence, sleep, stiffness, and treatment burden were on the research agenda.

CONCLUSION: The updated PsA Core Domain Set was endorsed at OMERACT 2016. Next steps for the PsA working group include evaluation of PsA outcome measures and development of a PsA Core Outcome Measurement Set.

OriginalsprogEngelsk
TidsskriftJournal of Rheumatology
Vol/bind44
Udgave nummer10
Sider (fra-til)1522-1528
Antal sider7
ISSN0315-162X
DOI
StatusUdgivet - okt. 2017

ID: 52010338