@article{c2b978bf3d114c60853e88c44cb6e33a,
title = "Type 2 diabetes risk allele near CENTD2 is associated with decreased glucose-stimulated insulin release",
abstract = "By combining multiple genome-wide association (GWA) studies and comprehensive replication efforts, 12 novel type 2 diabetes associated loci have recently been discovered. Here we evaluate the effect of lead variants of these loci on estimates of insulin release and insulin resistance derived from an oral glucose tolerance test.",
keywords = "Adaptor Proteins, Signal Transducing, Adult, Alleles, Carrier Proteins, Cell Cycle Proteins, DNA-Binding Proteins, Diabetes Mellitus, Type 2, Dual-Specificity Phosphatases, Female, GTPase-Activating Proteins, Genome-Wide Association Study, Genotype, Glucose, Glucose Tolerance Test, HMGA2 Protein, Heat-Shock Proteins, Hepatocyte Nuclear Factor 1-alpha, Humans, Insulin, Insulin-Secreting Cells, KCNQ1 Potassium Channel, Male, Middle Aged, Mitogen-Activated Protein Kinase Phosphatases, Molecular Epidemiology, Nuclear Proteins, Sp Transcription Factors, Transcription Factors",
author = "T Nielsen and Spars{\o}, {Thomas Hempel} and Niels Grarup and T J{\o}rgensen and C Pisinger and Witte, {Daniel Rinse} and T Hansen and O Pedersen and {DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium}",
year = "2011",
doi = "10.1007/s00125-011-2054-3",
language = "English",
volume = "54",
pages = "1052--6",
journal = "Diabetologia",
issn = "0012-186X",
publisher = "Springer",
number = "5",
}