Twelve weeks treatment with the DPP-4 inhibitor, sitagliptin, prevents degradation of peptide YY and improves glucose and non-glucose induced insulin secretion in patients with type 2 diabetes mellitus

K Aaboe, F K Knop, Tina Vilsbøll, Carolyn F. Deacon, Jens Møller Holst, S Madsbad, T Krarup

104 Citationer (Scopus)

Abstract

To examine the effects of 12 weeks of treatment with the DPP-4 inhibitor, sitagliptin, on gastrointestinal hormone responses to a standardized mixed meal and beta cell secretory capacity, measured as glucose and non-glucose induced insulin secretion during a hyperglycaemic clamp, in patients with type 2 diabetes.
OriginalsprogEngelsk
TidsskriftDiabetes, Obesity and Metabolism
Vol/bind12
Udgave nummer4
Sider (fra-til)323-33
Antal sider11
ISSN1462-8902
DOI
StatusUdgivet - 1 apr. 2010

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