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Udgivet

Tumour necrosis factor-alpha infusion produced insulin resistance but no change in the incretin effect in healthy volunteers

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

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Vis graf over relationer
Type 2 diabetes mellitus (T2DM) is associated with peripheral insulin resistance, impaired incretin effect, and increased plasma levels of tumour necrosis factor-alpha (TNF-α). Although TNF-α infusion at a dose that induces systemic inflammation in healthy volunteers has been demonstrated to induce peripheral insulin resistance, the influence of this cytokine on the incretin effect is unknown.
OriginalsprogEngelsk
TidsskriftDiabetes - Metabolism: Research and Reviews (Print Edition)
Vol/bind29
Udgave nummer8
Sider (fra-til)655-63
Antal sider9
ISSN1520-7552
DOI
StatusUdgivet - nov. 2013

ID: 42239672