Triglyceride-mediated pathways and coronary disease: collaborative analysis of 101 studies

Nadeem Sarwar; Manjinder S Sandhu; Sally L Ricketts; Adam S Butterworth; Emanuele Di Angelantonio; S Matthijs Boekholdt; Willem Ouwehand; Hugh Watkins; Nilesh J Samani; Danish Saleheen; Debbie Lawlor; Muredach P Reilly; Aroon D Hingorani; Philippa J Talmud; John Danesh; Torben Jørgensen; Triglyceride Coronary Disease Genetics Consortium and Emerging Risk Factors Collaboration; Anne  Tybjærg-Hansen; Ruth Frikke-Schmidt; Børge G. Nordestgaard

doi:10.1016/S0140-6736(10)60545-4

Triglyceride-mediated pathways and coronary disease: collaborative analysis of 101 studies

Nadeem Sarwar, Manjinder S Sandhu, Sally L Ricketts, Adam S Butterworth, Emanuele Di Angelantonio, S Matthijs Boekholdt, Willem Ouwehand, Hugh Watkins, Nilesh J Samani, Danish Saleheen, Debbie Lawlor, Muredach P Reilly, Aroon D Hingorani, Philippa J Talmud, John Danesh, Torben Jørgensen, Triglyceride Coronary Disease Genetics Consortium and Emerging Risk Factors Collaboration, Anne Tybjærg-Hansen, Ruth Frikke-Schmidt, Børge G. Nordestgaard

Afdeling for Klinisk Biokemi

601 Citationer (Scopus)

Abstract

Whether triglyceride-mediated pathways are causally relevant to coronary heart disease is uncertain. We studied a genetic variant that regulates triglyceride concentration to help judge likelihood of causality.

Originalsprog	Engelsk
Tidsskrift	Lancet
Vol/bind	375
Udgave nummer	9726
Sider (fra-til)	1634-9
Antal sider	6
DOI	https://doi.org/10.1016/S0140-6736(10)60545-4
Status	Udgivet - 8 maj 2010

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10.1016/S0140-6736(10)60545-4

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Sarwar, N., Sandhu, M. S., Ricketts, S. L., Butterworth, A. S., Di Angelantonio, E., Boekholdt, S. M., Ouwehand, W., Watkins, H., Samani, N. J., Saleheen, D., Lawlor, D., Reilly, M. P., Hingorani, A. D., Talmud, P. J., Danesh, J., Jørgensen, T., Triglyceride Coronary Disease Genetics Consortium and Emerging Risk Factors Collaboration, Tybjærg-Hansen, A., Frikke-Schmidt, R., & Nordestgaard, B. G. (2010). Triglyceride-mediated pathways and coronary disease: collaborative analysis of 101 studies. Lancet, 375(9726), 1634-9. https://doi.org/10.1016/S0140-6736(10)60545-4

Sarwar, N, Sandhu, MS, Ricketts, SL, Butterworth, AS, Di Angelantonio, E, Boekholdt, SM, Ouwehand, W, Watkins, H, Samani, NJ, Saleheen, D, Lawlor, D, Reilly, MP, Hingorani, AD, Talmud, PJ, Danesh, J, Jørgensen, T, Triglyceride Coronary Disease Genetics Consortium and Emerging Risk Factors Collaboration, Tybjærg-Hansen, A , Frikke-Schmidt, R & Nordestgaard, BG 2010, 'Triglyceride-mediated pathways and coronary disease: collaborative analysis of 101 studies', Lancet, bind 375, nr. 9726, s. 1634-9. https://doi.org/10.1016/S0140-6736(10)60545-4

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title = "Triglyceride-mediated pathways and coronary disease: collaborative analysis of 101 studies",

abstract = "Whether triglyceride-mediated pathways are causally relevant to coronary heart disease is uncertain. We studied a genetic variant that regulates triglyceride concentration to help judge likelihood of causality.",

author = "Nadeem Sarwar and Sandhu, {Manjinder S} and Ricketts, {Sally L} and Butterworth, {Adam S} and {Di Angelantonio}, Emanuele and Boekholdt, {S Matthijs} and Willem Ouwehand and Hugh Watkins and Samani, {Nilesh J} and Danish Saleheen and Debbie Lawlor and Reilly, {Muredach P} and Hingorani, {Aroon D} and Talmud, {Philippa J} and John Danesh and Torben J{\o}rgensen and {Triglyceride Coronary Disease Genetics Consortium and Emerging Risk Factors Collaboration} and Anne Tybj{\ae}rg-Hansen and Ruth Frikke-Schmidt and Nordestgaard, {B{\o}rge G.}",

year = "2010",

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doi = "10.1016/S0140-6736(10)60545-4",

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TY - JOUR

T1 - Triglyceride-mediated pathways and coronary disease: collaborative analysis of 101 studies

AU - Sarwar, Nadeem

AU - Sandhu, Manjinder S

AU - Ricketts, Sally L

AU - Butterworth, Adam S

AU - Di Angelantonio, Emanuele

AU - Boekholdt, S Matthijs

AU - Ouwehand, Willem

AU - Watkins, Hugh

AU - Samani, Nilesh J

AU - Saleheen, Danish

AU - Lawlor, Debbie

AU - Reilly, Muredach P

AU - Hingorani, Aroon D

AU - Talmud, Philippa J

AU - Danesh, John

AU - Jørgensen, Torben

AU - Triglyceride Coronary Disease Genetics Consortium and Emerging Risk Factors Collaboration

AU - Tybjærg-Hansen, Anne

AU - Frikke-Schmidt, Ruth

AU - Nordestgaard, Børge G.

PY - 2010/5/8

Y1 - 2010/5/8

N2 - Whether triglyceride-mediated pathways are causally relevant to coronary heart disease is uncertain. We studied a genetic variant that regulates triglyceride concentration to help judge likelihood of causality.

AB - Whether triglyceride-mediated pathways are causally relevant to coronary heart disease is uncertain. We studied a genetic variant that regulates triglyceride concentration to help judge likelihood of causality.

U2 - 10.1016/S0140-6736(10)60545-4

DO - 10.1016/S0140-6736(10)60545-4

M3 - Journal article

C2 - 20452521

SN - 1474-547X

VL - 375

SP - 1634

EP - 1639

JO - Lancet

JF - Lancet

IS - 9726

ER -

Triglyceride-mediated pathways and coronary disease: collaborative analysis of 101 studies

Abstract

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