Trial sequential analyses of meta-analyses of complications in laparoscopic vs. small-incision cholecystectomy: more randomized patients are needed

Frederik Keus; Jørn Wetterslev; Christian Gluud; Hein G Gooszen; Cornelis JHM van Laarhoven

doi:10.1016/j.jclinepi.2009.08.023

Trial sequential analyses of meta-analyses of complications in laparoscopic vs. small-incision cholecystectomy: more randomized patients are needed

Frederik Keus, Jørn Wetterslev, Christian Gluud, Hein G Gooszen, Cornelis JHM van Laarhoven

Copenhagen Trial Unit Rigshospitalet

19 Citationer (Scopus)

Abstract

Conclusions based on meta-analyses of randomized trials carry a status of "truth." Methodological components may identify trials with systematic errors ("bias"). Trial sequential analysis (TSA) evaluates random errors in meta-analysis. We analyzed meta-analyses on laparoscopic vs. small-incision cholecystectomy regarding different outcome measures for the occurrence of type I errors.

Originalsprog	Engelsk
Tidsskrift	Journal of Clinical Epidemiology
Vol/bind	63
Udgave nummer	3
Sider (fra-til)	246-56
Antal sider	11
ISSN	0895-4356
DOI	https://doi.org/10.1016/j.jclinepi.2009.08.023
Status	Udgivet - 1 mar. 2010

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10.1016/j.jclinepi.2009.08.023

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Trial sequential analyses of meta-analyses of complications in laparoscopic vs. small-incision cholecystectomy: more randomized patients are needed. / Keus, Frederik; Wetterslev, Jørn ; Gluud, Christian et al.

I: Journal of Clinical Epidemiology, Bind 63, Nr. 3, 01.03.2010, s. 246-56.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

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AU - Gluud, Christian

AU - Gooszen, Hein G

AU - JHM van Laarhoven, Cornelis

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AB - Conclusions based on meta-analyses of randomized trials carry a status of "truth." Methodological components may identify trials with systematic errors ("bias"). Trial sequential analysis (TSA) evaluates random errors in meta-analysis. We analyzed meta-analyses on laparoscopic vs. small-incision cholecystectomy regarding different outcome measures for the occurrence of type I errors.

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Trial sequential analyses of meta-analyses of complications in laparoscopic vs. small-incision cholecystectomy: more randomized patients are needed

Abstract

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