TY - JOUR
T1 - Treatment Patterns and Clinical Outcomes of Chronic Urticaria
T2 - Two-year Follow-up Results from the Scandinavian AWARE Study
AU - Thomsen, Simon F
AU - Pritzier, Ellen C
AU - Anderson, Chris D
AU - Juvik, Siri
AU - Baust, Nicolas V
AU - Dodge, Rikke
AU - Dahlborn, Anna-Karin
AU - Vestergaard, Christian
PY - 2022/4/7
Y1 - 2022/4/7
N2 - The AWARE (A World-wide Antihistamine-Refractory chronic urticaria patient Evaluation) study investigated outcomes in patients with chronic urticaria refractory to H1-antihistamine. The objective of the current study was to analyse the effects of treatment on patients' symptoms and quality of life for a period of up to 2 years. Over the 2 years, there was clear improvement in the high rates of disease burden from baseline, as evidenced by lower scores for disease severity scales, better quality of life, and a decreasing rate of medical resource utilization. However, this is the result of treatment adherence to the guidelines in highly specialized Scandinavian urticaria centres, and has its basis in the relatively low treatment intensity and control at enrolment. There is a need for greater adherence to the treatment guidelines and better management of antihistamine-refractory chronic urticaria.
AB - The AWARE (A World-wide Antihistamine-Refractory chronic urticaria patient Evaluation) study investigated outcomes in patients with chronic urticaria refractory to H1-antihistamine. The objective of the current study was to analyse the effects of treatment on patients' symptoms and quality of life for a period of up to 2 years. Over the 2 years, there was clear improvement in the high rates of disease burden from baseline, as evidenced by lower scores for disease severity scales, better quality of life, and a decreasing rate of medical resource utilization. However, this is the result of treatment adherence to the guidelines in highly specialized Scandinavian urticaria centres, and has its basis in the relatively low treatment intensity and control at enrolment. There is a need for greater adherence to the treatment guidelines and better management of antihistamine-refractory chronic urticaria.
KW - Chronic Disease
KW - Chronic Urticaria/diagnosis
KW - Follow-Up Studies
KW - Histamine H1 Antagonists/adverse effects
KW - Humans
KW - Quality of Life
KW - Urticaria/chemically induced
UR - http://www.scopus.com/inward/record.url?scp=85128248249&partnerID=8YFLogxK
U2 - 10.2340/actadv.v102.1620
DO - 10.2340/actadv.v102.1620
M3 - Journal article
C2 - 35166853
SN - 0001-5555
VL - 102
SP - adv00689
JO - Acta Dermato-Venereologica
JF - Acta Dermato-Venereologica
M1 - adv00689
ER -