Treatment of neonatal sepsis with intravenous immune globulin

Peter Brocklehurst, Barbara Farrell, Andrew King, Edmund Juszczak, Brian Darlow, Khalid Haque, Alison Salt, Ben Stenson, William Tarnow-Mordi, INIS Collaborative Group, Gorm Greisen, Jes Reinholdt

252 Citationer (Scopus)

Abstract

Neonatal sepsis is a major cause of death and complications despite antibiotic treatment. Effective adjunctive treatments are needed. Newborn infants are relatively deficient in endogenous immunoglobulin. Meta-analyses of trials of intravenous immune globulin for suspected or proven neonatal sepsis suggest a reduced rate of death from any cause, but the trials have been small and have varied in quality.
OriginalsprogEngelsk
TidsskriftNew England Journal of Medicine
Vol/bind365
Udgave nummer13
Sider (fra-til)1201-11
Antal sider11
ISSN0028-4793
DOI
StatusUdgivet - 2011

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