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Treatment of HNF1A-MODY with SGLT2 inhibition
Henrik Maagensen
Steno Diabetes Center Copenhagen
4
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Keyphrases
Sodium-glucose Cotransporter
100%
HNF1A-MODY
100%
Sodium-glucose Cotransporter 2 Inhibitors (SGLT2i)
50%
Urinary Glucose Excretion
25%
Glucose-lowering Drugs
25%
HNF1A
25%
Empagliflozin
25%
Monogenic Diabetes
25%
Diabetes
16%
Type 2 Diabetes Prevention
16%
Glycaemia
16%
Disease Variants
16%
No Significant Difference
8%
Placebo
8%
Placebo-controlled
8%
Drug Use
8%
Randomized Trial
8%
Glucose Transport
8%
Type 2 Diabetes Mellitus (T2DM)
8%
Insulin
8%
β-cell Function
8%
Randomized Double-blind
8%
Clinical Application
8%
Drug Class
8%
Glucose-insulin System
8%
Transcription Factor
8%
Early Onset
8%
Continuous Glucose Monitoring
8%
Hyperglycemic Clamp
8%
Impaired Insulin Secretion
8%
Non-insulin
8%
Safety Issues
8%
Glucosuria
8%
Distinct Subtypes
8%
Large Degree
8%
Renal Glucose Reabsorption
8%
Glucose Threshold
8%
Patients with Diabetes
8%
Well Tolerated
8%
Mean Blood Glucose
8%
Distinct Phenotype
8%
Renal Threshold for Glucose
8%
Biochemistry, Genetics and Molecular Biology
Cotransporter
100%
HNF1A
100%
Glucose
100%
Maturity Onset Diabetes of the Young
100%
Sodium-Glucose Cotransporter 2 Inhibitors
40%
Glucose Urine Level
20%
Glucose Blood Level
13%
Insulin
13%
Glucose Transport
6%
Cell Function
6%
Insulin Release
6%
Transcription Factors
6%