Treatment influencing down-staging in EORTC Melanoma Group sentinel node histological protocol compared with complete step-sectioning: a national multicentre study

Rikke Riber-Hansen, Nina Hastrup, Ole Clemmensen, Nille Behrendt, Siri Klausen, Mette Ramsing, Eva Spaun, Stephen Jacques Hamilton-Dutoit, Torben Steiniche

17 Citationer (Scopus)

Abstract

Metastasis size in melanoma sentinel lymph nodes (SLNs) is an emerging prognostic factor. Two European melanoma treatment trials include SLN metastasis diameters as inclusion criteria. Whilst diameter estimates are sensitive to the number of sections examined, the level of this bias is largely unknown. We performed a prospective multicentre study to compare the European Organisation for Research and Treatment of Cancer (EORTC) recommended protocol with a protocol of complete step-sectioning.
OriginalsprogEngelsk
TidsskriftEuropean Journal of Cancer
Vol/bind48
Udgave nummer3
Sider (fra-til)347-52
Antal sider6
ISSN0959-8049
DOI
StatusUdgivet - 2012

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