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Transgene mus som sygdomsmodeller

Mikkel Bruhn Schuster, Bo Torben Porse

Abstract

Transgenic animal models have proven to be useful tools in understanding both basic biology and the events associated with disease. Recent technical advances in the area of genomic manipulation in combination with the availability of the human and murine genomic sequences now allow the precise tailoring of the mouse genome. In this review we describe a few systems in which transgenic animal models have been employed for the purpose of studying the etiology of human diseases.

Bidragets oversatte titelTransgenic mice as disease models
OriginalsprogDansk
TidsskriftUgeskrift for Laeger
Vol/bind165
Udgave nummer8
Sider (fra-til)793-6
Antal sider4
ISSN0041-5782
StatusUdgivet - 17 feb. 2003
Udgivet eksterntJa

Emneord

  • Animals
  • Disease Models, Animal
  • Humans
  • Mice
  • Mice, Transgenic/genetics

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