Forskning
Udskriv Udskriv
Switch language
Region Hovedstaden - en del af Københavns Universitetshospital
Udgivet

Transcutaneous oxygen tension in imminent foot gangrene

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Harvard

APA

CBE

MLA

Vancouver

Author

Bibtex

@article{3f5301198954438d8651061a412ca79f,
title = "Transcutaneous oxygen tension in imminent foot gangrene",
abstract = "Transcutaneous oxygen tension at 44 degree C and maximal isotope clearance (90m Tc-pretechnetate + histramine) just proximal to the 1st toe and systolic toe blood pressure (strain gauge) were studied on a tilt table in patients with various degrees of obstructive arteriosclerotic disease. In legs with moderate obstruction, the oxygen tension reached zero at a toe systolic blood pressure of 5--10 mmHg (tilt toe up) and reached arterial oxygen tension at about 50 to 70 mmHg (tilt toe down). In legs withsevere arterial obstruction and ischaemic rest pain, oxygen tension rose from zero not before systolic toe blood pressure reached 20--50 mmHg. Significant isotope clearance was seen at pressures below the limits just mentioned for both types of patients. This phenomenon here seen of a perfusion without oxygen supply is explained by a gas leak (rendered significant because of the slow flow rate) from the arterioles into the tissue sink and counter current gas shunting. The hypoxia in spite of a positive perfusion pressure up to 50 mmHg explains our experience that ischemic ulcers in feet such low pressures never heal.",
keywords = "Aged, Blood Gas Analysis, Blood Pressure, Electrodes, Female, Foot, Gangrene, Humans, Male, Middle Aged, Oxygen, Partial Pressure",
author = "T{\o}nnesen, {K H}",
year = "1978",
language = "English",
volume = "68",
pages = "107--10",
journal = "Acta Anaesthesiologica Scandinavica, Supplement",
issn = "0515-2720",
publisher = "Blackwell Munksgaard",

}

RIS

TY - JOUR

T1 - Transcutaneous oxygen tension in imminent foot gangrene

AU - Tønnesen, K H

PY - 1978

Y1 - 1978

N2 - Transcutaneous oxygen tension at 44 degree C and maximal isotope clearance (90m Tc-pretechnetate + histramine) just proximal to the 1st toe and systolic toe blood pressure (strain gauge) were studied on a tilt table in patients with various degrees of obstructive arteriosclerotic disease. In legs with moderate obstruction, the oxygen tension reached zero at a toe systolic blood pressure of 5--10 mmHg (tilt toe up) and reached arterial oxygen tension at about 50 to 70 mmHg (tilt toe down). In legs withsevere arterial obstruction and ischaemic rest pain, oxygen tension rose from zero not before systolic toe blood pressure reached 20--50 mmHg. Significant isotope clearance was seen at pressures below the limits just mentioned for both types of patients. This phenomenon here seen of a perfusion without oxygen supply is explained by a gas leak (rendered significant because of the slow flow rate) from the arterioles into the tissue sink and counter current gas shunting. The hypoxia in spite of a positive perfusion pressure up to 50 mmHg explains our experience that ischemic ulcers in feet such low pressures never heal.

AB - Transcutaneous oxygen tension at 44 degree C and maximal isotope clearance (90m Tc-pretechnetate + histramine) just proximal to the 1st toe and systolic toe blood pressure (strain gauge) were studied on a tilt table in patients with various degrees of obstructive arteriosclerotic disease. In legs with moderate obstruction, the oxygen tension reached zero at a toe systolic blood pressure of 5--10 mmHg (tilt toe up) and reached arterial oxygen tension at about 50 to 70 mmHg (tilt toe down). In legs withsevere arterial obstruction and ischaemic rest pain, oxygen tension rose from zero not before systolic toe blood pressure reached 20--50 mmHg. Significant isotope clearance was seen at pressures below the limits just mentioned for both types of patients. This phenomenon here seen of a perfusion without oxygen supply is explained by a gas leak (rendered significant because of the slow flow rate) from the arterioles into the tissue sink and counter current gas shunting. The hypoxia in spite of a positive perfusion pressure up to 50 mmHg explains our experience that ischemic ulcers in feet such low pressures never heal.

KW - Aged

KW - Blood Gas Analysis

KW - Blood Pressure

KW - Electrodes

KW - Female

KW - Foot

KW - Gangrene

KW - Humans

KW - Male

KW - Middle Aged

KW - Oxygen

KW - Partial Pressure

M3 - Journal article

C2 - 279191

VL - 68

SP - 107

EP - 110

JO - Acta Anaesthesiologica Scandinavica, Supplement

JF - Acta Anaesthesiologica Scandinavica, Supplement

SN - 0515-2720

ER -

ID: 39050694