TY - JOUR
T1 - Transcatheter Intervention for Coarctation of the Aorta
T2 - A Nordic Population-Based Registry With Long-Term Follow-Up
AU - Eriksson, Peter
AU - Pihkala, Jaana
AU - Jensen, Annette S
AU - Dohlen, Gaute
AU - Liuba, Petru
AU - Wahlander, Hakan
AU - Sjoberg, Gunnar
AU - Hlebowicz, Joanna
AU - Furenas, Eva
AU - Leirgul, Elisabeth
AU - Settergren, Magnus
AU - Vithessonthi, Kanyalak
AU - Nielsen, Niels-Erik
AU - Christersson, Christina
AU - Sondergaard, Lars
AU - Sinisalo, Juha
AU - Nielsen-Kudsk, Jens Erik
AU - Dellborg, Mikael
AU - Larsen, Signe H
N1 - Copyright © 2023 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.
PY - 2023/2/27
Y1 - 2023/2/27
N2 - BACKGROUND: Coarctation of the aorta (CoA), a congenital narrowing of the proximal descending thoracic aorta, is a relatively common form of congenital heart disease. Untreated significant CoA has a major impact on morbidity and mortality. In the past 3 decades, transcatheter intervention (TCI) for CoA has evolved as an alternative to surgery.OBJECTIVES: The authors report on all TCIs for CoA performed from 2000 to 2016 in 4 countries covering 25 million inhabitants, with a mean follow-up duration of 6.9 years.METHODS: During the study period, 683 interventions were performed on 542 patients.RESULTS: The procedural success rate was 88%, with 9% considered partly successful. Complications at the intervention site occurred in 3.5% of interventions and at the access site in 3.5%. There was no in-hospital mortality. During follow-up, TCI for CoA reduced the presence of hypertension significantly from 73% to 34%, but despite this, many patients remained hypertensive and in need of continuous antihypertensive treatment. Moreover, 8% to 9% of patients needed aortic and/or aortic valve surgery during follow-up.CONCLUSIONS: TCI for CoA can be performed with a low risk for complications. Lifetime follow-up after TCI for CoA seems warranted.
AB - BACKGROUND: Coarctation of the aorta (CoA), a congenital narrowing of the proximal descending thoracic aorta, is a relatively common form of congenital heart disease. Untreated significant CoA has a major impact on morbidity and mortality. In the past 3 decades, transcatheter intervention (TCI) for CoA has evolved as an alternative to surgery.OBJECTIVES: The authors report on all TCIs for CoA performed from 2000 to 2016 in 4 countries covering 25 million inhabitants, with a mean follow-up duration of 6.9 years.METHODS: During the study period, 683 interventions were performed on 542 patients.RESULTS: The procedural success rate was 88%, with 9% considered partly successful. Complications at the intervention site occurred in 3.5% of interventions and at the access site in 3.5%. There was no in-hospital mortality. During follow-up, TCI for CoA reduced the presence of hypertension significantly from 73% to 34%, but despite this, many patients remained hypertensive and in need of continuous antihypertensive treatment. Moreover, 8% to 9% of patients needed aortic and/or aortic valve surgery during follow-up.CONCLUSIONS: TCI for CoA can be performed with a low risk for complications. Lifetime follow-up after TCI for CoA seems warranted.
KW - catheter intervention
KW - coarctation of Aorta
KW - congenital heart disease
UR - http://www.scopus.com/inward/record.url?scp=85148647929&partnerID=8YFLogxK
U2 - 10.1016/j.jcin.2022.11.007
DO - 10.1016/j.jcin.2022.11.007
M3 - Journal article
C2 - 36858664
SN - 1936-8798
VL - 16
SP - 444
EP - 453
JO - JACC. Cardiovascular interventions
JF - JACC. Cardiovascular interventions
IS - 4
ER -