TY - JOUR
T1 - Training intensity and improvements in exercise capacity in elderly patients undergoing European cardiac rehabilitation - the EU-CaRE multicenter cohort study
AU - Marcin, Thimo
AU - Eser, Prisca
AU - Prescott, Eva
AU - Prins, Leonie F
AU - Kolkman, Evelien
AU - Bruins, Wendy
AU - van der Velde, Astrid E
AU - Peña Gil, Carlos
AU - Iliou, Marie-Christine
AU - Ardissino, Diego
AU - Zeymer, Uwe
AU - Meindersma, Esther P
AU - Van't Hof, Arnoud W J
AU - de Kluiver, Ed P
AU - Wilhelm, Matthias
PY - 2020
Y1 - 2020
N2 - OBJECTIVES: Guidelines for exercise intensity prescription in Cardiac Rehabilitation (CR) are inconsistent and have recently been discussed controversially. We aimed (1) to compare training intensities between European CR centres and (2) to assess associations between training intensity and improvement in peak oxygen consumption ([Formula: see text]O2) in elderly CR patients.METHODS: Peak [Formula: see text]O2, heart rate and work rate (WR) at the first and second ventilatory thresholds were measured at start of CR. Training heart rate was measured during three sessions spread over the CR. Multivariate models were used to compare training characteristics between centres and to assess the effect of training intensity on change in peak [Formula: see text]O2.RESULTS: Training intensity was measured in 1011 out of 1633 EU-CaRE patients in 7 of 8 centers and the first and secondary ventilatory threshold were identified in 1166 and 817 patients, respectively. The first and second ventilatory threshold were found at 44% (SD 16%) and 78% (SD 9%) of peak WR and 78% (SD 9%) and 89% (SD 5%) of peak heart rate, respectively. Training intensity and session duration varied significantly between centres but change in peak [Formula: see text]O2 over CR did not. Training above the first individual threshold (β 0.62, 95% confidence interval [0.25-1.02]) and increase in training volume per hour (β 0.06, 95%CI [0.01-0.12]) were associated with a higher change in peak [Formula: see text]O2.CONCLUSION: While training intensity and volume varied greatly amongst current European CR programs, changes in peak [Formula: see text]O2 were similar and the effect of training characteristics on these changes were small.
AB - OBJECTIVES: Guidelines for exercise intensity prescription in Cardiac Rehabilitation (CR) are inconsistent and have recently been discussed controversially. We aimed (1) to compare training intensities between European CR centres and (2) to assess associations between training intensity and improvement in peak oxygen consumption ([Formula: see text]O2) in elderly CR patients.METHODS: Peak [Formula: see text]O2, heart rate and work rate (WR) at the first and second ventilatory thresholds were measured at start of CR. Training heart rate was measured during three sessions spread over the CR. Multivariate models were used to compare training characteristics between centres and to assess the effect of training intensity on change in peak [Formula: see text]O2.RESULTS: Training intensity was measured in 1011 out of 1633 EU-CaRE patients in 7 of 8 centers and the first and secondary ventilatory threshold were identified in 1166 and 817 patients, respectively. The first and second ventilatory threshold were found at 44% (SD 16%) and 78% (SD 9%) of peak WR and 78% (SD 9%) and 89% (SD 5%) of peak heart rate, respectively. Training intensity and session duration varied significantly between centres but change in peak [Formula: see text]O2 over CR did not. Training above the first individual threshold (β 0.62, 95% confidence interval [0.25-1.02]) and increase in training volume per hour (β 0.06, 95%CI [0.01-0.12]) were associated with a higher change in peak [Formula: see text]O2.CONCLUSION: While training intensity and volume varied greatly amongst current European CR programs, changes in peak [Formula: see text]O2 were similar and the effect of training characteristics on these changes were small.
KW - Aged
KW - Aged, 80 and over
KW - Cardiac Rehabilitation/methods
KW - Cohort Studies
KW - Europe
KW - Exercise/physiology
KW - Exercise Test/methods
KW - Exercise Therapy/methods
KW - Exercise Tolerance/physiology
KW - Female
KW - Heart Rate/physiology
KW - Humans
KW - Male
KW - Oxygen Consumption/physiology
KW - Prospective Studies
KW - Pulmonary Gas Exchange/physiology
UR - https://www.scopus.com/pages/publications/85096044062
U2 - 10.1371/journal.pone.0242503
DO - 10.1371/journal.pone.0242503
M3 - Journal article
C2 - 33186408
SN - 1932-6203
VL - 15
SP - e0242503
JO - PLoS One
JF - PLoS One
IS - 11
ER -