Forskning
Udskriv Udskriv
Switch language
Region Hovedstaden - en del af Københavns Universitetshospital
Udgivet

Tissue Doppler echocardiography improves the diagnosis of coronary artery stenosis in stable angina pectoris

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

DOI

  1. Duration of early systolic lengthening: prognostic potential in the general population

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Myocardial performance index by tissue Doppler echocardiography predicts adverse events in patients with atrial fibrillation

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Screening relatives in arrhythmogenic right ventricular cardiomyopathy: yield of imaging and electrical investigations

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. Risk of COVID-19 in health-care workers in Denmark: an observational cohort study

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Acute COVID-19 and the Incidence of Ischemic Stroke and Acute Myocardial Infarction

    Publikation: Bidrag til tidsskriftLetterForskningpeer review

Vis graf over relationer
Aim To determine if colour tissue Doppler imaging (TDI) performed at rest in patients with suspected stable angina pectoris (SAP) is able to predict the presence of significant coronary artery disease (CAD). METHODS AND RESULTS: This study comprises 296 consecutive patients with clinically suspected SAP, no previous cardiac history, and a normal ejection fraction. All patients were examined by colour TDI, exercise electrocardiogram (ECG), and coronary angiography (CAG). Regional longitudinal systolic (s'), early diastolic (e'), and late diastolic (a') myocardial velocities were measured by colour TDI at six mitral annular sites and averaged to provide global estimates. Duke score (DS), including ST depression, chest pain, and exercise capacity, was used as the outcome of the exercise ECG. Patients with an area stenosis of ≥70% in at least one epicardial coronary artery were categorized as having a significant CAD (n= 108) and were compared with patients without significant CAD (n= 188). Both e' [odds ratio (OR): 1.5 (1.1-1.9, P <0.01) per cm/s decrease] and s' [OR: 1.7 (1.1-2.5, P <0.05) per cm/s decrease] remained independent predictors of CAD after multivariable adjustment for baseline, exercise ECG, and conventional echocardiographic parameters. Area under the receiver operating characteristic curve (AUC) for exercise ECG and TDI in combination was significantly higher than AUC for exercise ECG alone (0.84 vs. 0.79, P <0.01). CONCLUSION: In patients with suspected SAP colour TDI performed at rest is an independent predictor of significant CAD, and colour TDI improves the diagnostic performance of exercise ECG.
OriginalsprogEngelsk
TidsskriftEuropean heart journal cardiovascular Imaging
Vol/bind13
Udgave nummer9
Sider (fra-til)724-9
Antal sider6
DOI
StatusUdgivet - 2012

ID: 36484497