Forskning
Udskriv Udskriv
Switch language
Region Hovedstaden - en del af Københavns Universitetshospital
Udgivet

Timing of surgical site infection and pulmonary complications after laparotomy

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

DOI

  1. Update on the role of ultrasound guided radiofrequency ablation for thyroid nodule treatment

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Impaired blood supply in the colonic anastomosis in mice compromises healing

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Decreased leakage rate of colonic anastomoses by tachosil coating: an experimental study

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. Short-stay unit hospitalisation vs. standard care outcomes in older internal medicine patients-a randomised clinical trial

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Recommendations for the nomenclature of cognitive change associated with anaesthesia and surgery-2018

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Recommendations for the nomenclature of cognitive change associated with anaesthesia and surgery-2018

    Publikation: Bidrag til tidsskriftReviewForskningpeer review

  4. Recommendations for the Nomenclature of Cognitive Change Associated with Anaesthesia and Surgery-2018

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  5. Gennemgang af Early Warning Score til forebyggelse af uventet kritisk sygdom og død

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Vis graf over relationer

BACKGROUND: Surgical site infection (SSI) and other postoperative complications are associated with high costs, morbidity, secondary surgery, and mortality. Many studies have identified factors that may prevent SSI and pulmonary complications, but it is important to know when they in fact occur. The aim of this study was to investigate the diagnostic timing of surgical site infections and pulmonary complications after laparotomy.

MATERIAL AND METHODS: This is a secondary analysis of the PROXI trial which was a randomized clinical trial conducted in 1400 patients undergoing elective or emergent laparotomy. Patients were randomly allocated to either 80% or 30% perioperative inspiratory oxygen fraction.

RESULTS: SSI or pulmonary complications were diagnosed in 24.2% (95% CI: 22.0%-26.5%) of the patients at a median of 9 days [IQR: 5-15] after surgery. Most common was surgical site infection (19.6%); median time 10 days after surgery [IQR: 7-18]. The corresponding figures for anastomotic leakage was 5.7%, 8 days [IQR: 6-10]; pneumonia 3.5%, 5 days [IQR: 3-9]; and respiratory failure 2.3%, 3 days [IQR: 1-8]. The oxygen allocation was not significantly related to time of diagnosis for postoperative surgical site infections or pulmonary complications.

CONCLUSION: A high percentage of patients undergoing laparotomy develop a postoperative complication. This study adds new knowledge by identifying time intervals within which medical professionals should be aware of surgical site infections and pulmonary complications in order to initiate appropriate treatment of the patients.

OriginalsprogEngelsk
TidsskriftInternational Surgery
Vol/bind52
Sider (fra-til)56-60
ISSN0020-8868
DOI
StatusUdgivet - 15 feb. 2018

ID: 52764761