Time trends of short-term mortality for octogenarians undergoing a colorectal resection in North Europe

Y H M Claassen; E Bastiaannet; E van Eycken; N Van Damme; A Martling; R Johansson; L H Iversen; P Ingeholm; V E P P Lemmens; G J Liefers; F A Holman; J W T Dekker; J E A Portielje; H J Rutten; C J H van de Velde

doi:10.1016/j.ejso.2019.03.041

Time trends of short-term mortality for octogenarians undergoing a colorectal resection in North Europe

Y H M Claassen, E Bastiaannet, E van Eycken, N Van Damme, A Martling, R Johansson, L H Iversen, P Ingeholm, V E P P Lemmens, G J Liefers, F A Holman, J W T Dekker, J E A Portielje, H J Rutten, C J H van de Velde

Patologi

12 Citationer (Scopus)

Abstract

BACKGROUND: Decreased cancer specific survival in older colorectal patients is mainly due to mortality in the first year, emphasizing the importance of the first postoperative year. This study aims to gain an overview and time trends of short-term mortality in octogenarians (≥80 years) with colorectal cancer across four North European countries.

METHODS: Patients of 80 years or older, operated for colorectal cancer (stage I-III) between 2005 and 2014, were included. Population-based cohorts from Belgium, Denmark, the Netherlands, and Sweden were collected. Separately for colon- and rectal cancer, 30-day, 90-day, one-year, and excess one-year mortality were calculated. Also, short-term mortality over three time periods (2005-2008, 2009-2011, 2012-2014) was analyzed.

RESULTS: In total, 35,158 colon cancer patients and 10,144 rectal cancer patients were included. For colon cancer, 90-day mortality rate was highest in Denmark (15%) and lowest in Sweden (8%). For rectal cancer, 90-day mortality rate was highest in Belgium (11%) and lowest in Sweden (7%). One-year excess mortality rate of colon cancer patients decreased from 2005 to 2008 to 2012-2014 for all countries (Belgium: 17%-11%, Denmark: 21%-15%, the Netherlands: 18%-10%, and Sweden: 10%-8%). For rectal cancer, from 2005 to 2008 to 2012-2014 one-year excess mortality rate decreased in the Netherlands from 16% to 7% and Sweden: 8%-2%).

CONCLUSIONS: Short-term mortality rates were high in octogenarians operated for colorectal cancer. Short-term mortality rates differ across four North European countries, but decreased over time for both colon and rectal cancer patients in all countries.

Originalsprog	Engelsk
Tidsskrift	European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
Vol/bind	45
Udgave nummer	8
Sider (fra-til)	1396-1402
Antal sider	7
ISSN	0748-7983
DOI	https://doi.org/10.1016/j.ejso.2019.03.041
Status	Udgivet - aug. 2019

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10.1016/j.ejso.2019.03.041

Citationsformater

Claassen, Y. H. M., Bastiaannet, E., van Eycken, E., Van Damme, N., Martling, A., Johansson, R., Iversen, L. H., Ingeholm, P., Lemmens, V. E. P. P., Liefers, G. J., Holman, F. A., Dekker, J. W. T., Portielje, J. E. A., Rutten, H. J., & van de Velde, C. J. H. (2019). Time trends of short-term mortality for octogenarians undergoing a colorectal resection in North Europe. European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 45(8), 1396-1402. https://doi.org/10.1016/j.ejso.2019.03.041

Time trends of short-term mortality for octogenarians undergoing a colorectal resection in North Europe. / Claassen, Y H M; Bastiaannet, E; van Eycken, E et al.
I: European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, Bind 45, Nr. 8, 08.2019, s. 1396-1402.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

Claassen, YHM, Bastiaannet, E, van Eycken, E, Van Damme, N, Martling, A, Johansson, R, Iversen, LH, Ingeholm, P, Lemmens, VEPP, Liefers, GJ, Holman, FA, Dekker, JWT, Portielje, JEA, Rutten, HJ & van de Velde, CJH 2019, 'Time trends of short-term mortality for octogenarians undergoing a colorectal resection in North Europe', European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, bind 45, nr. 8, s. 1396-1402. https://doi.org/10.1016/j.ejso.2019.03.041

Claassen YHM, Bastiaannet E, van Eycken E, Van Damme N, Martling A, Johansson R et al. Time trends of short-term mortality for octogenarians undergoing a colorectal resection in North Europe. European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology. 2019 aug.;45(8):1396-1402. doi: 10.1016/j.ejso.2019.03.041

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title = "Time trends of short-term mortality for octogenarians undergoing a colorectal resection in North Europe",

abstract = "BACKGROUND: Decreased cancer specific survival in older colorectal patients is mainly due to mortality in the first year, emphasizing the importance of the first postoperative year. This study aims to gain an overview and time trends of short-term mortality in octogenarians (≥80 years) with colorectal cancer across four North European countries.METHODS: Patients of 80 years or older, operated for colorectal cancer (stage I-III) between 2005 and 2014, were included. Population-based cohorts from Belgium, Denmark, the Netherlands, and Sweden were collected. Separately for colon- and rectal cancer, 30-day, 90-day, one-year, and excess one-year mortality were calculated. Also, short-term mortality over three time periods (2005-2008, 2009-2011, 2012-2014) was analyzed.RESULTS: In total, 35,158 colon cancer patients and 10,144 rectal cancer patients were included. For colon cancer, 90-day mortality rate was highest in Denmark (15%) and lowest in Sweden (8%). For rectal cancer, 90-day mortality rate was highest in Belgium (11%) and lowest in Sweden (7%). One-year excess mortality rate of colon cancer patients decreased from 2005 to 2008 to 2012-2014 for all countries (Belgium: 17%-11%, Denmark: 21%-15%, the Netherlands: 18%-10%, and Sweden: 10%-8%). For rectal cancer, from 2005 to 2008 to 2012-2014 one-year excess mortality rate decreased in the Netherlands from 16% to 7% and Sweden: 8%-2%).CONCLUSIONS: Short-term mortality rates were high in octogenarians operated for colorectal cancer. Short-term mortality rates differ across four North European countries, but decreased over time for both colon and rectal cancer patients in all countries.",

author = "Claassen, {Y H M} and E Bastiaannet and {van Eycken}, E and {Van Damme}, N and A Martling and R Johansson and Iversen, {L H} and P Ingeholm and Lemmens, {V E P P} and Liefers, {G J} and Holman, {F A} and Dekker, {J W T} and Portielje, {J E A} and Rutten, {H J} and {van de Velde}, {C J H}",

note = "Copyright {\textcopyright} 2019. Published by Elsevier Ltd.",

year = "2019",

month = aug,

doi = "10.1016/j.ejso.2019.03.041",

language = "English",

volume = "45",

pages = "1396--1402",

journal = "European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology",

issn = "0748-7983",

publisher = "W.B. Saunders Ltd",

number = "8",

}

TY - JOUR

T1 - Time trends of short-term mortality for octogenarians undergoing a colorectal resection in North Europe

AU - Claassen, Y H M

AU - Bastiaannet, E

AU - van Eycken, E

AU - Van Damme, N

AU - Martling, A

AU - Johansson, R

AU - Iversen, L H

AU - Ingeholm, P

AU - Lemmens, V E P P

AU - Liefers, G J

AU - Holman, F A

AU - Dekker, J W T

AU - Portielje, J E A

AU - Rutten, H J

AU - van de Velde, C J H

PY - 2019/8

Y1 - 2019/8

N2 - BACKGROUND: Decreased cancer specific survival in older colorectal patients is mainly due to mortality in the first year, emphasizing the importance of the first postoperative year. This study aims to gain an overview and time trends of short-term mortality in octogenarians (≥80 years) with colorectal cancer across four North European countries.METHODS: Patients of 80 years or older, operated for colorectal cancer (stage I-III) between 2005 and 2014, were included. Population-based cohorts from Belgium, Denmark, the Netherlands, and Sweden were collected. Separately for colon- and rectal cancer, 30-day, 90-day, one-year, and excess one-year mortality were calculated. Also, short-term mortality over three time periods (2005-2008, 2009-2011, 2012-2014) was analyzed.RESULTS: In total, 35,158 colon cancer patients and 10,144 rectal cancer patients were included. For colon cancer, 90-day mortality rate was highest in Denmark (15%) and lowest in Sweden (8%). For rectal cancer, 90-day mortality rate was highest in Belgium (11%) and lowest in Sweden (7%). One-year excess mortality rate of colon cancer patients decreased from 2005 to 2008 to 2012-2014 for all countries (Belgium: 17%-11%, Denmark: 21%-15%, the Netherlands: 18%-10%, and Sweden: 10%-8%). For rectal cancer, from 2005 to 2008 to 2012-2014 one-year excess mortality rate decreased in the Netherlands from 16% to 7% and Sweden: 8%-2%).CONCLUSIONS: Short-term mortality rates were high in octogenarians operated for colorectal cancer. Short-term mortality rates differ across four North European countries, but decreased over time for both colon and rectal cancer patients in all countries.

AB - BACKGROUND: Decreased cancer specific survival in older colorectal patients is mainly due to mortality in the first year, emphasizing the importance of the first postoperative year. This study aims to gain an overview and time trends of short-term mortality in octogenarians (≥80 years) with colorectal cancer across four North European countries.METHODS: Patients of 80 years or older, operated for colorectal cancer (stage I-III) between 2005 and 2014, were included. Population-based cohorts from Belgium, Denmark, the Netherlands, and Sweden were collected. Separately for colon- and rectal cancer, 30-day, 90-day, one-year, and excess one-year mortality were calculated. Also, short-term mortality over three time periods (2005-2008, 2009-2011, 2012-2014) was analyzed.RESULTS: In total, 35,158 colon cancer patients and 10,144 rectal cancer patients were included. For colon cancer, 90-day mortality rate was highest in Denmark (15%) and lowest in Sweden (8%). For rectal cancer, 90-day mortality rate was highest in Belgium (11%) and lowest in Sweden (7%). One-year excess mortality rate of colon cancer patients decreased from 2005 to 2008 to 2012-2014 for all countries (Belgium: 17%-11%, Denmark: 21%-15%, the Netherlands: 18%-10%, and Sweden: 10%-8%). For rectal cancer, from 2005 to 2008 to 2012-2014 one-year excess mortality rate decreased in the Netherlands from 16% to 7% and Sweden: 8%-2%).CONCLUSIONS: Short-term mortality rates were high in octogenarians operated for colorectal cancer. Short-term mortality rates differ across four North European countries, but decreased over time for both colon and rectal cancer patients in all countries.

U2 - 10.1016/j.ejso.2019.03.041

DO - 10.1016/j.ejso.2019.03.041

M3 - Journal article

C2 - 31003722

SN - 0748-7983

VL - 45

SP - 1396

EP - 1402

JO - European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

JF - European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

IS - 8

ER -

Time trends of short-term mortality for octogenarians undergoing a colorectal resection in North Europe

Abstract

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