Time-dependent and anisotropic diffusion in the heart: linear and spherical tensor encoding with varying degree of motion compensation

Samo Lasič, Henrik Lundell, Filip Szczepankiewicz, Markus Nilsson, Jurgen E. Schneider, Irvin Teh

Abstract

Spherical tensor encoding (STE) can potentially shorten acquisition of mean diffusivity (MD) compared to the traditional linear tensor encoding (LTE). To avoid negative effects of motion, e.g. in the heart, motion compensation is needed. However, motion compensation requires altering diffusion gradient waveforms and their sensitivities to time-dependent diffusion. To exclude motion, we first investigated LTE and STE with different degrees of motion compensation in ex vivo pig hearts. We observed significantly different MD, which can be attributed to time-dependent diffusion and microscopic diffusion anisotropy. Our analysis suggests that time-dependent diffusion is a critical determinant of MD in the myocardium.

OriginalsprogEngelsk
TitelProceedings of the 2020 ISMRM & SMRT Virtual Conference & Exhibition
Antal sider3
ForlagThe International Society for Magnetic Resonance in Medicine
Publikationsdato2020
Sider1-3
Artikelnummer4300
StatusUdgivet - 2020
BegivenhedISMRM & SMRT Virtual Conference & Exhibition 2020 - Virtual conference
Varighed: 8 aug. 202014 aug. 2020
https://www.ismrm.org/20m/

Konference

KonferenceISMRM & SMRT Virtual Conference & Exhibition 2020
LokationVirtual conference
Periode08/08/202014/08/2020
Internetadresse

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