Three-dimensional reconstructions of intrahepatic bile duct tubulogenesis in human liver

Peter Siig Vestentoft, Peter Jelnes, Branden Michael Hopkinson, Ben Vainer, Kjeld Møllgård, Bjørn Quistorff, Hanne Cathrine Bisgaard

31 Citationer (Scopus)
115 Downloads (Pure)

Abstract

During liver development, intrahepatic bile ducts are thought to arise by a unique asymmetric mode of cholangiocyte tubulogenesis characterized by a series of remodeling stages. Moreover, in liver diseases, cells lining the Canals of Hering can proliferate and generate new hepatic tissue. The aim of this study was to develop protocols for three-dimensional visualization of protein expression, hepatic portal structures and human hepatic cholangiocyte tubulogenesis.
OriginalsprogEngelsk
TidsskriftB M C Developmental Biology
Vol/bind11
Sider (fra-til)56
ISSN1471-213X
DOI
StatusUdgivet - 2011

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