The T allele of rs7903146 TCF7L2 is associated with impaired insulinotropic action of incretin hormones, reduced 24 h profiles of plasma insulin and glucagon, and increased hepatic glucose production in young healthy men

K Pilgaard; C B Jensen; J H Schou; V Lyssenko; L Wegner; Charlotte Brøns; Tina Vilsbøll; T Hansen; S Madsbad; Jens Møller Holst; Anders Vølund; P Poulsen; L Groop; O Pedersen; Allan Arthur Vaag

doi:10.1007/s00125-009-1307-x

The T allele of rs7903146 TCF7L2 is associated with impaired insulinotropic action of incretin hormones, reduced 24 h profiles of plasma insulin and glucagon, and increased hepatic glucose production in young healthy men

K Pilgaard, C B Jensen, J H Schou, V Lyssenko, L Wegner, Charlotte Brøns, Tina Vilsbøll, T Hansen, S Madsbad, Jens Møller Holst, Anders Vølund, P Poulsen, L Groop, O Pedersen, Allan Arthur Vaag

Endokrinologisk Forskningsenhed AHH

123 Citationer (Scopus)

Abstract

We studied the physiological, metabolic and hormonal mechanisms underlying the elevated risk of type 2 diabetes in carriers of TCF7L2 gene.

Originalsprog	Engelsk
Tidsskrift	Diabetologia
Vol/bind	52
Udgave nummer	7
Sider (fra-til)	1298-307
Antal sider	10
ISSN	0012-186X
DOI	https://doi.org/10.1007/s00125-009-1307-x
Status	Udgivet - 1 jul. 2009

Adgang til dokumentet

10.1007/s00125-009-1307-x

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Citationsformater

Pilgaard, K., Jensen, C. B., Schou, J. H., Lyssenko, V., Wegner, L., Brøns, C., Vilsbøll, T., Hansen, T., Madsbad, S., Holst, J. M., Vølund, A., Poulsen, P., Groop, L., Pedersen, O., & Vaag, A. A. (2009). The T allele of rs7903146 TCF7L2 is associated with impaired insulinotropic action of incretin hormones, reduced 24 h profiles of plasma insulin and glucagon, and increased hepatic glucose production in young healthy men. Diabetologia, 52(7), 1298-307. https://doi.org/10.1007/s00125-009-1307-x

The T allele of rs7903146 TCF7L2 is associated with impaired insulinotropic action of incretin hormones, reduced 24 h profiles of plasma insulin and glucagon, and increased hepatic glucose production in young healthy men. / Pilgaard, K; Jensen, C B; Schou, J H et al.
I: Diabetologia, Bind 52, Nr. 7, 01.07.2009, s. 1298-307.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

Pilgaard, K, Jensen, CB, Schou, JH, Lyssenko, V, Wegner, L, Brøns, C , Vilsbøll, T, Hansen, T, Madsbad, S, Holst, JM, Vølund, A, Poulsen, P, Groop, L, Pedersen, O & Vaag, AA 2009, 'The T allele of rs7903146 TCF7L2 is associated with impaired insulinotropic action of incretin hormones, reduced 24 h profiles of plasma insulin and glucagon, and increased hepatic glucose production in young healthy men', Diabetologia, bind 52, nr. 7, s. 1298-307. https://doi.org/10.1007/s00125-009-1307-x

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abstract = "We studied the physiological, metabolic and hormonal mechanisms underlying the elevated risk of type 2 diabetes in carriers of TCF7L2 gene.",

author = "K Pilgaard and Jensen, {C B} and Schou, {J H} and V Lyssenko and L Wegner and Charlotte Br{\o}ns and Tina Vilsb{\o}ll and T Hansen and S Madsbad and Holst, {Jens M{\o}ller} and Anders V{\o}lund and P Poulsen and L Groop and O Pedersen and Vaag, {Allan Arthur}",

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AU - Jensen, C B

AU - Schou, J H

AU - Lyssenko, V

AU - Wegner, L

AU - Brøns, Charlotte

AU - Vilsbøll, Tina

AU - Hansen, T

AU - Madsbad, S

AU - Holst, Jens Møller

AU - Vølund, Anders

AU - Poulsen, P

AU - Groop, L

AU - Pedersen, O

AU - Vaag, Allan Arthur

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N2 - We studied the physiological, metabolic and hormonal mechanisms underlying the elevated risk of type 2 diabetes in carriers of TCF7L2 gene.

AB - We studied the physiological, metabolic and hormonal mechanisms underlying the elevated risk of type 2 diabetes in carriers of TCF7L2 gene.

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