The role of the mast cell in pigmentation disorders

Valdemar Wendelboe Nielsen, Simon Francis Thomsen

Abstract

The mast cell is a critical mediator of the inflammatory response by secreting histamine. While histamine is currently not regarded as a melanogen, recent studies have shown histamine release to induce melanogenesis, melanocyte proliferation and migration. Herein, we discuss the current evidence of the complex relationship between the mast cell and melanocyte, and its impact in pigmentation disorders.
OriginalsprogDansk
TidsskriftPigment International
Vol/bind8
Udgave nummer2
Sider (fra-til)73-75
StatusUdgivet - 2021

Citationsformater