The role of miRNAs in human papilloma virus (HPV)-associated cancers: bridging between HPV-related head and neck cancer and cervical cancer

C B Lajer; E Garnæs; L Friis-Hansen; Bodil Norrild; M H Therkildsen; M Glud; M Rossing; H Lajer; D Svane; Line Skotte; L Specht; C Buchwald; F C Nielsen

doi:10.1038/bjc.2012.109

The role of miRNAs in human papilloma virus (HPV)-associated cancers: bridging between HPV-related head and neck cancer and cervical cancer

C B Lajer
, E Garnæs
, L Friis-Hansen
, Bodil Norrild
, M H Therkildsen
, M Glud
, M Rossing
, H Lajer
, D Svane
, Line Skotte
, L Specht
, C Buchwald
, F C Nielsen

206 Citationer (Scopus)

Abstract

Although the role of human papilloma virus (HPV) in cervical squamous cell carcinoma (CSCC) is well established, the role in head and neck SCC (HNSCC) is less clear. MicroRNAs (miRNAs) have a role in the cancer development, and HPV status may affect the miRNA expression pattern in HNSCC. To explore the influence of HPV in HNSCC, we made a comparative miRNA profile of HPV-positive (HPV+) and HPV-negative (HPV-) HNSCC against CSCC.

Originalsprog	Engelsk
Tidsskrift	British Journal of Cancer
Vol/bind	106
Udgave nummer	9
Sider (fra-til)	1526-34
Antal sider	9
ISSN	0007-0920
DOI	https://doi.org/10.1038/bjc.2012.109
Status	Udgivet - 2012

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10.1038/bjc.2012.109

Citationsformater

Lajer, C. B., Garnæs, E., Friis-Hansen, L., Norrild, B., Therkildsen, M. H., Glud, M., Rossing, M., Lajer, H., Svane, D., Skotte, L., Specht, L., Buchwald, C., & Nielsen, F. C. (2012). The role of miRNAs in human papilloma virus (HPV)-associated cancers: bridging between HPV-related head and neck cancer and cervical cancer. British Journal of Cancer, 106(9), 1526-34. https://doi.org/10.1038/bjc.2012.109

Lajer, CB, Garnæs, E, Friis-Hansen, L, Norrild, B, Therkildsen, MH, Glud, M , Rossing, M, Lajer, H, Svane, D, Skotte, L, Specht, L , Buchwald, C & Nielsen, FC 2012, 'The role of miRNAs in human papilloma virus (HPV)-associated cancers: bridging between HPV-related head and neck cancer and cervical cancer', British Journal of Cancer, bind 106, nr. 9, s. 1526-34. https://doi.org/10.1038/bjc.2012.109

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title = "The role of miRNAs in human papilloma virus (HPV)-associated cancers: bridging between HPV-related head and neck cancer and cervical cancer",

abstract = "Although the role of human papilloma virus (HPV) in cervical squamous cell carcinoma (CSCC) is well established, the role in head and neck SCC (HNSCC) is less clear. MicroRNAs (miRNAs) have a role in the cancer development, and HPV status may affect the miRNA expression pattern in HNSCC. To explore the influence of HPV in HNSCC, we made a comparative miRNA profile of HPV-positive (HPV+) and HPV-negative (HPV-) HNSCC against CSCC.",

keywords = "Adolescent, Carcinoma, Squamous Cell, Case-Control Studies, Child, DNA, Viral, Female, Gene Expression Profiling, Head and Neck Neoplasms, Humans, Laser Capture Microdissection, Male, MicroRNAs, Middle Aged, Neoplasm Staging, Oligonucleotide Array Sequence Analysis, Papillomaviridae, Papillomavirus Infections, Prognosis, RNA, Messenger, Real-Time Polymerase Chain Reaction, Tumor Markers, Biological",

author = "Lajer, \{C B\} and E Garn{\ae}s and L Friis-Hansen and Bodil Norrild and Therkildsen, \{M H\} and M Glud and M Rossing and H Lajer and D Svane and Line Skotte and L Specht and C Buchwald and Nielsen, \{F C\}",

year = "2012",

doi = "10.1038/bjc.2012.109",

language = "English",

volume = "106",

pages = "1526--34",

journal = "British Journal of Cancer",

issn = "0007-0920",

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TY - JOUR

T1 - The role of miRNAs in human papilloma virus (HPV)-associated cancers

T2 - bridging between HPV-related head and neck cancer and cervical cancer

AU - Lajer, C B

AU - Garnæs, E

AU - Friis-Hansen, L

AU - Norrild, Bodil

AU - Therkildsen, M H

AU - Glud, M

AU - Rossing, M

AU - Lajer, H

AU - Svane, D

AU - Skotte, Line

AU - Specht, L

AU - Buchwald, C

AU - Nielsen, F C

PY - 2012

Y1 - 2012

N2 - Although the role of human papilloma virus (HPV) in cervical squamous cell carcinoma (CSCC) is well established, the role in head and neck SCC (HNSCC) is less clear. MicroRNAs (miRNAs) have a role in the cancer development, and HPV status may affect the miRNA expression pattern in HNSCC. To explore the influence of HPV in HNSCC, we made a comparative miRNA profile of HPV-positive (HPV+) and HPV-negative (HPV-) HNSCC against CSCC.

AB - Although the role of human papilloma virus (HPV) in cervical squamous cell carcinoma (CSCC) is well established, the role in head and neck SCC (HNSCC) is less clear. MicroRNAs (miRNAs) have a role in the cancer development, and HPV status may affect the miRNA expression pattern in HNSCC. To explore the influence of HPV in HNSCC, we made a comparative miRNA profile of HPV-positive (HPV+) and HPV-negative (HPV-) HNSCC against CSCC.

KW - Adolescent

KW - Carcinoma, Squamous Cell

KW - Case-Control Studies

KW - Child

KW - DNA, Viral

KW - Female

KW - Gene Expression Profiling

KW - Head and Neck Neoplasms

KW - Humans

KW - Laser Capture Microdissection

KW - Male

KW - MicroRNAs

KW - Middle Aged

KW - Neoplasm Staging

KW - Oligonucleotide Array Sequence Analysis

KW - Papillomaviridae

KW - Papillomavirus Infections

KW - Prognosis

KW - RNA, Messenger

KW - Real-Time Polymerase Chain Reaction

KW - Tumor Markers, Biological

U2 - 10.1038/bjc.2012.109

DO - 10.1038/bjc.2012.109

M3 - Journal article

C2 - 22472886

SN - 0007-0920

VL - 106

SP - 1526

EP - 1534

JO - British Journal of Cancer

JF - British Journal of Cancer

IS - 9

ER -

The role of miRNAs in human papilloma virus (HPV)-associated cancers: bridging between HPV-related head and neck cancer and cervical cancer

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