The role of miRNAs in human papilloma virus (HPV)-associated cancers: bridging between HPV-related head and neck cancer and cervical cancer

C B Lajer, E Garnæs, L Friis-Hansen, Bodil Norrild, M H Therkildsen, M Glud, M Rossing, H Lajer, D Svane, Line Skotte, L Specht, C Buchwald, F C Nielsen

Abstract

Although the role of human papilloma virus (HPV) in cervical squamous cell carcinoma (CSCC) is well established, the role in head and neck SCC (HNSCC) is less clear. MicroRNAs (miRNAs) have a role in the cancer development, and HPV status may affect the miRNA expression pattern in HNSCC. To explore the influence of HPV in HNSCC, we made a comparative miRNA profile of HPV-positive (HPV+) and HPV-negative (HPV-) HNSCC against CSCC.
OriginalsprogEngelsk
TidsskriftB J C
Vol/bind106
Udgave nummer9
Sider (fra-til)1526-34
Antal sider9
ISSN0007-0920
DOI
StatusUdgivet - 2012

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