Forskning
Udskriv Udskriv
Switch language
Region Hovedstaden - en del af Københavns Universitetshospital
Udgivet

The role of infectious agents in cancer of the ocular region

Publikation: Bidrag til tidsskriftReviewpeer review

DOI

  1. APMIS pandemic editorial

    Publikation: Bidrag til tidsskriftLederpeer review

  2. Pandemics: past, present, future: That is like choosing between cholera and plague

    Publikation: Bidrag til tidsskriftReviewpeer review

  3. Status: nosocomial transmission and prevention of SARS-CoV-2 in a Danish context

    Publikation: Bidrag til tidsskriftReviewpeer review

  4. Beta-hemolytic streptococci A, C and G are susceptible to cloxacillin

    Publikation: Bidrag til tidsskriftLetterpeer review

  1. Ultraviolet radiation drives mutations in a subset of mucosal melanomas

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Seasonal variation in biopsy-proven giant cell arteritis in Eastern Denmark from 1990-2018

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Ocular adnexal lymphoma in Denmark: a nationwide study of 387 cases from 1980 to 2017

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Vis graf over relationer

The purpose of the study was to investigate the association between infectious agents and the development of cancer in the ocular adnexa. A comprehensive literary study was carried out, reviewing and summarizing previous reports on the topic. A broad range of malignancies of the ocular adnexa are associated with infectious agents. A strong association and possible causal relationship between the infectious agent and the development of ocular adnexal cancer are seen in Merkel cell carcinoma (Merkel cell polyomavirus), Burkitt lymphoma (Epstein-Barr virus) and Kaposi sarcoma (human herpesvirus 8). Infection with Chlamydia psittaci has been associated with the development of extranodal marginal zone B-cell lymphoma in Italy. Human papillomavirus infection has been associated with the development of squamous cell carcinomas of the ocular adnexa, although with a highly variable reported prevalence. By exploring the role of infectious agents in the ocular adnexa and the mechanism by which they contribute to oncogenesis, the diagnostics, management and prevention of these malignancies may also improve. Antibiotic treatment and vaccines against infectious agents may be valuable in future treatment. Additionally, the presence of infectious agents within the tumours may have a prognostic or predictive value.

OriginalsprogEngelsk
TidsskriftAPMIS - Journal of Pathology, Microbiology and Immunology
Vol/bind128
Udgave nummer2
Sider (fra-til)136-149
Antal sider14
ISSN0903-4641
DOI
StatusUdgivet - feb. 2020

Bibliografisk note

© 2020 APMIS. Published by John Wiley & Sons Ltd.

ID: 61961566