Forskning
Udskriv Udskriv
Switch language
Region Hovedstaden - en del af Københavns Universitetshospital
Udgivet

The risk of long-term bowel dysfunction after resection for sigmoid adenocarcinoma: a cross sectional survey comparing complete mesocolic excision with conventional surgery

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

DOI

  1. Benefit from extended surveillance interval on colorectal cancer risk in Lynch syndrome

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Self-reported sexual dysfunction in patients with rectal cancer

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Expert consensus on a train-the-trainer curriculum for robotic colorectal surgery

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  4. Urinary dysfunction in patients with rectal cancer: a prospective cohort study

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  5. Why still in hospital after laparoscopic colorectal surgery within an enhanced recovery programme?

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. Effect of dosage of 17ß-estradiol on uterine growth in Turner syndrome - a randomized controlled clinical pilot trial

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Sår og benigne abdominalkirurgiske hudlidelser

    Publikation: Bidrag til bog/antologi/rapportBidrag til bog/antologiUndervisningpeer review

  3. The incomplete story of complete mesocolic excision - Authors' reply

    Publikation: Bidrag til tidsskriftLetterForskning

  4. 5-year outcome after complete mesocolic excision for right-sided colon cancer: a population-based cohort study

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  5. The REAL (REctal Anastomotic Leak) score for prediction of anastomotic leak after rectal cancer surgery

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Vis graf over relationer

AIM: To investigate if complete mesocolic excision (CME) might carry a higher risk of bowel dysfunction and subsequent reduction in quality of life when compared with conventional resection.

METHOD: A cross-sectional questionnaire study based on data from a national survey regarding long-term bowel function and a population-based cohort study comparing CME (study group) with conventional resections (control group). 622 patients undergoing elective resections for stage I-III sigmoid adenocarcinoma at four university colorectal centres between June 2008 and December 2014 were eligible to receive the questionnaire in mid-November 2015. Primary outcomes were four or more bowel movements daily, nocturnal bowel movements, unproductive call to stool, obstructive sensation and impact of bowel function on quality of life (QOL).

RESULTS: 127 (69.0%) and 289 (66.0%) patients in the study and control groups respectively responded to the questionnaire after medians of 4.41 (IQR 2.50; 5.83) and 4.57 (3.15; 5.82) years respectively (p = 0.048). CME was not associated with: increased risk of four or more bowel movements daily (adjusted OR 1.14 (95% CI 0.59-2.14; p = 0.68)), nocturnal bowel movements (adjusted OR 1.31 (0.66-2.53; p = 0.43)), unproductive call to stool (adjusted OR 0.99 (0.54-1.77; p = 0.97)), or obstructive sensation (adjusted OR 1.01 (0.56-1.78; p = 0.96)). While one in five patients in both groups had moderate to severe impact of bowel function on QOL, there was no association to CME.

CONCLUSION: For patients with sigmoid cancer, CME is associated with neither higher risk of bowel dysfunction nor impaired QOL. This article is protected by copyright. All rights reserved.

OriginalsprogEngelsk
TidsskriftColorectal Disease
Vol/bind20
Udgave nummer9
Sider (fra-til)0256-0266
ISSN1462-8910
DOI
StatusUdgivet - 2018

ID: 54747642