The prognostic value of the suPARnostic ELISA in HIV-1 infected individuals is not affected by uPAR promoter polymorphisms

Uffe V Schneider, Rikke Nielsen, Court Pedersen, Jesper Eugen-Olsen

16 Citationer (Scopus)

Abstract

High blood levels of soluble urokinase Plasminogen Activator Receptor (suPAR) are associated with poor outcomes in human immunodeficiency-1 (HIV-1) infected individuals. Research on the clinical value of suPAR in HIV-1 infection led to the development of the suPARnostic(R) assay for commercial use in 2006. The aim of this study was to: 1) Evaluate the prognostic value of the new suPARnostic assay and 2) Determine whether polymorphisms in the active promoter of uPAR influences survival and/or suPAR values in HIV-1 patients who are antiretroviral therapy (ART) naive.
OriginalsprogEngelsk
TidsskriftBMC Infectious Disease
Vol/bind7
Udgave nummer1
Sider (fra-til)134
DOI
StatusUdgivet - 2007

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