The pro-inflammatory biomarker soluble urokinase plasminogen activator receptor (suPAR) is associated with incident type 2 diabetes among overweight but not obese individuals with impaired glucose regulation: effect modification by smoking and body weight status

A Heraclides; T M Jensen; S S Rasmussen; J Eugen-Olsen; Steen B Haugaard; Knut Borch-Johnsen; Annelli Sandbæk; Thyge Peter Lauritzen; Daniel Rinse Witte

doi:10.1007/s00125-013-2914-0

The pro-inflammatory biomarker soluble urokinase plasminogen activator receptor (suPAR) is associated with incident type 2 diabetes among overweight but not obese individuals with impaired glucose regulation: effect modification by smoking and body weight status

A Heraclides
, T M Jensen
, S S Rasmussen
, J Eugen-Olsen
, Steen B Haugaard
, Knut Borch-Johnsen
, Annelli Sandbæk
, Thyge Peter Lauritzen
, Daniel Rinse Witte

40 Citationer (Scopus)

Abstract

Recent evidence links the soluble urokinase plasminogen activator receptor (suPAR), a stable biomarker of systemic immune activation, to several chronic diseases, including type 2 diabetes. suPAR is also associated with adiposity and smoking. We hypothesised that this biomarker would be linked to incident type 2 diabetes in individuals with impaired glucose regulation and that this association would be modified by smoking and body weight status.

Originalsprog	Engelsk
Tidsskrift	Diabetologia
Vol/bind	56
Udgave nummer	7
Sider (fra-til)	1542-6
Antal sider	5
ISSN	0012-186X
DOI	https://doi.org/10.1007/s00125-013-2914-0
Status	Udgivet - jul. 2013

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10.1007/s00125-013-2914-0

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Citationsformater

Heraclides, A., Jensen, T. M., Rasmussen, S. S., Eugen-Olsen, J., Haugaard, S. B., Borch-Johnsen, K., Sandbæk, A., Lauritzen, T. P., & Witte, D. R. (2013). The pro-inflammatory biomarker soluble urokinase plasminogen activator receptor (suPAR) is associated with incident type 2 diabetes among overweight but not obese individuals with impaired glucose regulation: effect modification by smoking and body weight status. Diabetologia, 56(7), 1542-6. https://doi.org/10.1007/s00125-013-2914-0

The pro-inflammatory biomarker soluble urokinase plasminogen activator receptor (suPAR) is associated with incident type 2 diabetes among overweight but not obese individuals with impaired glucose regulation: effect modification by smoking and body weight status. / Heraclides, A; Jensen, T M; Rasmussen, S S et al.
I: Diabetologia, Bind 56, Nr. 7, 07.2013, s. 1542-6.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

Heraclides, A, Jensen, TM, Rasmussen, SS, Eugen-Olsen, J, Haugaard, SB, Borch-Johnsen, K, Sandbæk, A, Lauritzen, TP & Witte, DR 2013, 'The pro-inflammatory biomarker soluble urokinase plasminogen activator receptor (suPAR) is associated with incident type 2 diabetes among overweight but not obese individuals with impaired glucose regulation: effect modification by smoking and body weight status', Diabetologia, bind 56, nr. 7, s. 1542-6. https://doi.org/10.1007/s00125-013-2914-0

Heraclides A, Jensen TM, Rasmussen SS, Eugen-Olsen J, Haugaard SB, Borch-Johnsen K et al. The pro-inflammatory biomarker soluble urokinase plasminogen activator receptor (suPAR) is associated with incident type 2 diabetes among overweight but not obese individuals with impaired glucose regulation: effect modification by smoking and body weight status. Diabetologia. 2013 jul.;56(7):1542-6. doi: 10.1007/s00125-013-2914-0

Heraclides, A ; Jensen, T M ; Rasmussen, S S et al. / The pro-inflammatory biomarker soluble urokinase plasminogen activator receptor (suPAR) is associated with incident type 2 diabetes among overweight but not obese individuals with impaired glucose regulation : effect modification by smoking and body weight status. I: Diabetologia. 2013 ; Bind 56, Nr. 7. s. 1542-6.

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abstract = "Recent evidence links the soluble urokinase plasminogen activator receptor (suPAR), a stable biomarker of systemic immune activation, to several chronic diseases, including type 2 diabetes. suPAR is also associated with adiposity and smoking. We hypothesised that this biomarker would be linked to incident type 2 diabetes in individuals with impaired glucose regulation and that this association would be modified by smoking and body weight status.",

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AU - Rasmussen, S S

AU - Eugen-Olsen, J

AU - Haugaard, Steen B

AU - Borch-Johnsen, Knut

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KW - Male

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