The pro-inflammatory biomarker soluble urokinase plasminogen activator receptor (suPAR) is associated with incident type 2 diabetes among overweight but not obese individuals with impaired glucose regulation: effect modification by smoking and body weight status

A Heraclides, T M Jensen, S S Rasmussen, J Eugen-Olsen, Steen B Haugaard, Knut Borch-Johnsen, Annelli Sandbæk, Thyge Peter Lauritzen, Daniel Rinse Witte

37 Citationer (Scopus)

Abstract

Recent evidence links the soluble urokinase plasminogen activator receptor (suPAR), a stable biomarker of systemic immune activation, to several chronic diseases, including type 2 diabetes. suPAR is also associated with adiposity and smoking. We hypothesised that this biomarker would be linked to incident type 2 diabetes in individuals with impaired glucose regulation and that this association would be modified by smoking and body weight status.
OriginalsprogEngelsk
TidsskriftDiabetologia
Vol/bind56
Udgave nummer7
Sider (fra-til)1542-6
Antal sider5
ISSN0012-186X
DOI
StatusUdgivet - jul. 2013

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