TY - JOUR
T1 - The presence of comorbidity in Tourette syndrome increases the need for pharmacological treatment
AU - Debes, Nanette M M M
AU - Hjalgrim, Helle
AU - Skov, Liselotte
N1 - Keywords: Adolescent; Anticonvulsants; Attention Deficit Disorder with Hyperactivity; Brain; Central Nervous System Stimulants; Child; Child, Preschool; Cognitive Therapy; Cohort Studies; Comorbidity; Denmark; Dietary Supplements; Female; Humans; Interviews as Topic; Male; Neuropharmacology; Obsessive-Compulsive Disorder; Scandinavia; Serotonin Uptake Inhibitors; Tourette Syndrome; Treatment Outcome; Young Adult
PY - 2009
Y1 - 2009
N2 - Tourette syndrome is often accompanied by other syndromes, like attention-deficit hyperactivity disorder (ADHD) and obsessive-compulsive disorder, and its treatment is symptomatic. Because there are no European guidelines for pharmacological treatment in Tourette syndrome, we wanted to contribute to a better insight into the common practice in Scandinavia. Furthermore, we wanted to elaborate the influence of the presence of comorbidities and of the severity of tics on pharmacological treatment. We have examined the frequency, art, and reason for pharmacological treatment in a Danish clinical cohort of 314 children with Tourette syndrome. In total, 60.5% of the children once had received pharmacological treatment. Mostly, the treatment was started because of tics or ADHD. If ADHD or obsessive-compulsive disorder were present, more children received pharmacological treatment and more different agents were tried. The children who received pharmacological treatment had more severe tics than those without medication.
AB - Tourette syndrome is often accompanied by other syndromes, like attention-deficit hyperactivity disorder (ADHD) and obsessive-compulsive disorder, and its treatment is symptomatic. Because there are no European guidelines for pharmacological treatment in Tourette syndrome, we wanted to contribute to a better insight into the common practice in Scandinavia. Furthermore, we wanted to elaborate the influence of the presence of comorbidities and of the severity of tics on pharmacological treatment. We have examined the frequency, art, and reason for pharmacological treatment in a Danish clinical cohort of 314 children with Tourette syndrome. In total, 60.5% of the children once had received pharmacological treatment. Mostly, the treatment was started because of tics or ADHD. If ADHD or obsessive-compulsive disorder were present, more children received pharmacological treatment and more different agents were tried. The children who received pharmacological treatment had more severe tics than those without medication.
U2 - 10.1177/0883073808331363
DO - 10.1177/0883073808331363
M3 - Journal article
C2 - 19494355
SN - 0883-0738
VL - 24
SP - 1504
EP - 1512
JO - Journal of Child Neurology
JF - Journal of Child Neurology
IS - 12
ER -