The PNPLA3 rs738409 G-Allele Associates with Reduced Fasting Serum Triglyceride and Serum Cholesterol in Danes with Impaired Glucose Regulation

Nikolaj Thure Krarup; Niels Grarup; Karina Banasik; Martin Friedrichsen; Kristine Færch; Camilla Helene Sandholt; Torben Jørgensen; Pernille Poulsen; Daniel Rinse Witte; Allan Vaag; Thorkild Sørensen; Oluf Borbye Pedersen; Torben Hansen

doi:10.1371/journal.pone.0040376

The PNPLA3 rs738409 G-Allele Associates with Reduced Fasting Serum Triglyceride and Serum Cholesterol in Danes with Impaired Glucose Regulation

Nikolaj Thure Krarup, Niels Grarup, Karina Banasik, Martin Friedrichsen, Kristine Færch, Camilla Helene Sandholt, Torben Jørgensen, Pernille Poulsen, Daniel Rinse Witte, Allan Vaag, Thorkild Sørensen, Oluf Borbye Pedersen, Torben Hansen

36 Citationer (Scopus)

Abstract

Non-alcoholic fatty liver disease (NAFLD) is a common condition, associated with hepatic insulin resistance and the metabolic syndrome including hyperglycaemia and dyslipidemia. We aimed at studying the potential impact of the NAFLD-associated PNPLA3 rs738409 G-allele on NAFLD-related metabolic traits in hyperglycaemic individuals.

Originalsprog	Engelsk
Tidsskrift	P L o S One
Vol/bind	7
Udgave nummer	7
Sider (fra-til)	e40376
ISSN	1932-6203
DOI	https://doi.org/10.1371/journal.pone.0040376
Status	Udgivet - 2012

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Krarup, N. T., Grarup, N., Banasik, K., Friedrichsen, M., Færch, K., Sandholt, C. H., Jørgensen, T., Poulsen, P., Witte, D. R., Vaag, A., Sørensen, T., Pedersen, O. B., & Hansen, T. (2012). The PNPLA3 rs738409 G-Allele Associates with Reduced Fasting Serum Triglyceride and Serum Cholesterol in Danes with Impaired Glucose Regulation. P L o S One, 7(7), e40376. https://doi.org/10.1371/journal.pone.0040376

Krarup, NT, Grarup, N, Banasik, K, Friedrichsen, M, Færch, K, Sandholt, CH, Jørgensen, T, Poulsen, P, Witte, DR, Vaag, A, Sørensen, T, Pedersen, OB & Hansen, T 2012, 'The PNPLA3 rs738409 G-Allele Associates with Reduced Fasting Serum Triglyceride and Serum Cholesterol in Danes with Impaired Glucose Regulation', P L o S One, bind 7, nr. 7, s. e40376. https://doi.org/10.1371/journal.pone.0040376

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abstract = "Non-alcoholic fatty liver disease (NAFLD) is a common condition, associated with hepatic insulin resistance and the metabolic syndrome including hyperglycaemia and dyslipidemia. We aimed at studying the potential impact of the NAFLD-associated PNPLA3 rs738409 G-allele on NAFLD-related metabolic traits in hyperglycaemic individuals.",

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AU - Krarup, Nikolaj Thure

AU - Grarup, Niels

AU - Banasik, Karina

AU - Friedrichsen, Martin

AU - Færch, Kristine

AU - Sandholt, Camilla Helene

AU - Jørgensen, Torben

AU - Poulsen, Pernille

AU - Witte, Daniel Rinse

AU - Vaag, Allan

AU - Sørensen, Thorkild

AU - Pedersen, Oluf Borbye

AU - Hansen, Torben

PY - 2012

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N2 - Non-alcoholic fatty liver disease (NAFLD) is a common condition, associated with hepatic insulin resistance and the metabolic syndrome including hyperglycaemia and dyslipidemia. We aimed at studying the potential impact of the NAFLD-associated PNPLA3 rs738409 G-allele on NAFLD-related metabolic traits in hyperglycaemic individuals.

AB - Non-alcoholic fatty liver disease (NAFLD) is a common condition, associated with hepatic insulin resistance and the metabolic syndrome including hyperglycaemia and dyslipidemia. We aimed at studying the potential impact of the NAFLD-associated PNPLA3 rs738409 G-allele on NAFLD-related metabolic traits in hyperglycaemic individuals.

UR - https://www.scopus.com/pages/publications/84863618176

U2 - 10.1371/journal.pone.0040376

DO - 10.1371/journal.pone.0040376

M3 - Journal article

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The PNPLA3 rs738409 G-Allele Associates with Reduced Fasting Serum Triglyceride and Serum Cholesterol in Danes with Impaired Glucose Regulation

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