The Number of Signaling Pathways Altered by Driver Mutations in Chronic Lymphocytic Leukemia Impacts Disease Outcome

Keyphrases

• Signaling Pathway 100%
• Disease Outcome 100%
• Chronic Lymphocytic Leukemia 100%
• Driver mutations 100%
• Delayed Diagnosis 30%
• Time to First Treatment 30%
• Clinical Impact 20%
• Recurrent mutation 20%
• Mutated Genes 20%
• Altered Pathway 20%
• Low Risk 10%
• Clinical Course 10%
• Newly Diagnosed 10%
• Clinical High Risk 10%
• Prognostic Value 10%
• Clinical Genetics 10%
• Overall Survival 10%
• Clinical Care 10%
• Gene mutation 10%
• Intermediate Risk 10%
• Low Burden 10%
• External Validation 10%
• Newly Diagnosed Patients 10%
• Genome Complexity 10%
• Pathway-based Approach 10%
• Next-generation Sequencing 10%
• Gene Panel 10%
• Leukemia Diagnosis 10%
• Gene Pathway 10%
• Personalized Follow-up 10%
• Molecular Prognostication 10%

Biochemistry, Genetics and Molecular Biology

• Signal Transduction 100%
• Mutated Genes 66%
• Prospective Study 33%
• Genetics 33%
• Gene Mutation 33%
• Overall Survival 33%
• Independent Pathway 33%
• IGHV@ 33%
• Next Generation Sequencing 33%