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Region Hovedstaden - en del af Københavns Universitetshospital
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The microRNA molecular signature of atypic and common acquired melanocytic nevi: differential expression of miR-125b and let-7c

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MicroRNAs (miRNAs) are small non-coding RNAs, which regulate gene expression through base pairing with mRNA and which are crucially involved in carcinogenesis (the so-called oncomiRs). We compared the miRNA signature between acquired melanocytic nevi showing clinical atypia (atypic nevi, AN) and common acquired nevi (common nevi, CN). We obtained miRNA profiles from 41 biopsies (22 AN and 19 CN) and showed that AN could be differentiated from CN on the basis of the expression of 36 miRNAs (false discovery rate
OriginalsprogEngelsk
TidsskriftExperimental Dermatology
Vol/bind20
Udgave nummer3
Sider (fra-til)278-80
Antal sider3
ISSN0906-6705
DOI
StatusUdgivet - 2011

ID: 33125542