The metabolic syndrome in HIV

Signe W Worm, Jens D Lundgren

    22 Citationer (Scopus)


    The metabolic syndrome (MS) is a term used to describe the clustering of risk factors for cardiovascular disease (CVD), including elevated triglyceride (TG), low high density lipoprotein cholesterol (HDL), hypertension, hyperglycemia/ insulin resistance and intra-abdominal obesity. This paper discusses why the prevalence of MS in the setting of HIV has been reported to range from 7-45% and how antiretroviral drugs might contribute to the development of MS. The MS has been reported to be a 'CVD risk enhancer', and much debate is ongoing on the independent risk of CVD associated with the MS. Based on a limited number of studies on MS in HIV with clinical end-points, there is no data to support that the MS is independently associated with an increased risk of CVD.
    TidsskriftBest Practice & Research: Clinical Endocrinology & Metabolism
    Udgave nummer3
    Sider (fra-til)479-86
    Antal sider8
    StatusUdgivet - 1 jun. 2011


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