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Region Hovedstaden - en del af Københavns Universitetshospital
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The Influence of Volume and Anatomic Location of Optic Disc Drusen on the Sensitivity of Autofluorescence

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. Ipsilateral Recurrence of Optic Disc Drusen-Associated Anterior Ischemic Optic Neuropathy in a 15-Year-Old Boy

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Optic Disc Drusen Associated Anterior Ischemic Optic Neuropathy: Prevalence of Comorbidities and Vascular Risk Factors

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Progression Over 5 Years of Prelaminar Hyperreflective Lines to Optic Disc Drusen in the Copenhagen Child Cohort 2000 Eye Study

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  4. Optic Disc Drusen in Children: The Copenhagen Child Cohort 2000 Eye Study

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. Ipsilateral Recurrence of Optic Disc Drusen-Associated Anterior Ischemic Optic Neuropathy in a 15-Year-Old Boy

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Optic disc drusen diagnosed by optical coherence tomography in a 3-year-old child

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Multiplexed optical coherence tomography imaging of optic disc drusen

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  4. Optic Disc Classification by Deep Learning versus Expert Neuro-Ophthalmologists

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Vis graf over relationer

BACKGROUND: Optic disc drusen (ODD) are acellular deposits in the optic nerve head. ODD can be diagnosed using different imaging modalities, including enhanced depth imaging optical coherence tomography (EDI-OCT) and autofluorescence (AF). It is unknown which factors determine the sensitivity of AF. The aim of this study was to investigate the effect of volume and anatomic location of ODD on the sensitivity of AF.

METHODS: Cross-sectional study.

RESULTS: A total of 38 patients (75 eyes) with ODD were included. In 12 of 75 eyes (16%) and in 11 of 38 patients (29%), EDI-OCT detected ODD that were not detected by AF. In 24 distinctly solitary ODD, both increase in ODD volume (P = 0.0388) and a more superficial ODD location (P < 0.0001) increased the possibility of AF detection of ODD, when performing a multivariate analysis.

CONCLUSIONS: EDI-OCT is superior to AF in the diagnosis of ODD. Volume and anatomic location of ODD have a significant impact on the sensitivity of AF.

OriginalsprogEngelsk
TidsskriftJournal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society
Vol/bind39
Udgave nummer1
Sider (fra-til)23-27
Antal sider5
ISSN1070-8022
DOI
StatusUdgivet - 2019

ID: 56583260