The importance of haemoglobin level and effect of transfusion in HNSCC patients treated with radiotherapy--results from the randomized DAHANCA 5 study

Camilla Molich Hoff, Hanne Sand Hansen, Marie Overgaard, Cai Grau, Jørgen Johansen, Jens Bentzen, Jens Overgaard

56 Citationer (Scopus)

Abstract

Patients with head and neck squamous cell carcinoma (HNSCC) and a low level of haemoglobin (Hb) often have a poor response to radiation which may be related to hypoxia induced radioresistance. The aim of the study was to evaluate the prognostic significance of low Hb level and its modification by transfusion in HNSCC patients treated with radiotherapy. The study was performed as a subrandomization in the DAHANCA 5 trial.
OriginalsprogEngelsk
TidsskriftRadiotherapy & Oncology
Vol/bind98
Udgave nummer1
Sider (fra-til)28-33
Antal sider6
ISSN0167-8140
DOI
StatusUdgivet - 2011

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