The effect of the oral PKC β inhibitor ruboxistaurin on vision loss in two phase 3 studies

Matthew J Sheetz; Lloyd Paul Aiello; Matthew D Davis; Ronald Danis; Toke Bek; Jose Cunha-Vaz; Nazila Shahri; Paul H Berg; MBDL and MBCU Study Groups

doi:10.1167/iovs.12-11055

The effect of the oral PKC β inhibitor ruboxistaurin on vision loss in two phase 3 studies

Matthew J Sheetz, Lloyd Paul Aiello, Matthew D Davis, Ronald Danis, Toke Bek, Jose Cunha-Vaz, Nazila Shahri, Paul H Berg, MBDL and MBCU Study Groups

Afdeling for Øjensygdomme HOC

61 Citationer (Scopus)

Abstract

To assess the effect of ruboxistaurin (RBX) on vision loss through a prospectively defined combined analysis of two phase 3 trials (MBDL and MBCU).

Originalsprog	Engelsk
Tidsskrift	Investigative ophthalmology & visual science
Vol/bind	54
Udgave nummer	3
Sider (fra-til)	1750-7
Antal sider	8
ISSN	0146-0404
DOI	https://doi.org/10.1167/iovs.12-11055
Status	Udgivet - mar. 2013

Adgang til dokumentet

10.1167/iovs.12-11055

Andre filer og links

Link to publication in Scopus

Citationsformater

@article{d3454d8da71a44adbefa1f34fe362f6f,

title = "The effect of the oral PKC β inhibitor ruboxistaurin on vision loss in two phase 3 studies",

abstract = "To assess the effect of ruboxistaurin (RBX) on vision loss through a prospectively defined combined analysis of two phase 3 trials (MBDL and MBCU).",

keywords = "Administration, Oral, Diabetic Retinopathy, Double-Blind Method, Enzyme Inhibitors, Female, Humans, Indoles, Macular Edema, Male, Maleimides, Middle Aged, Prospective Studies, Protein Kinase C, Questionnaires, Sickness Impact Profile, Tomography, Optical Coherence, Vision Disorders, Visual Acuity",

author = "Sheetz, \{Matthew J\} and Aiello, \{Lloyd Paul\} and Davis, \{Matthew D\} and Ronald Danis and Toke Bek and Jose Cunha-Vaz and Nazila Shahri and Berg, \{Paul H\} and \{MBDL and MBCU Study Groups\}",

year = "2013",

month = mar,

doi = "10.1167/iovs.12-11055",

language = "English",

volume = "54",

pages = "1750--7",

journal = "Investigative ophthalmology \& visual science",

issn = "0146-0404",

publisher = "Association for Research in Vision and Ophthalmology Inc.",

number = "3",

}

TY - JOUR

T1 - The effect of the oral PKC β inhibitor ruboxistaurin on vision loss in two phase 3 studies

AU - Sheetz, Matthew J

AU - Aiello, Lloyd Paul

AU - Davis, Matthew D

AU - Danis, Ronald

AU - Bek, Toke

AU - Cunha-Vaz, Jose

AU - Shahri, Nazila

AU - Berg, Paul H

AU - MBDL and MBCU Study Groups

PY - 2013/3

Y1 - 2013/3

N2 - To assess the effect of ruboxistaurin (RBX) on vision loss through a prospectively defined combined analysis of two phase 3 trials (MBDL and MBCU).

AB - To assess the effect of ruboxistaurin (RBX) on vision loss through a prospectively defined combined analysis of two phase 3 trials (MBDL and MBCU).

KW - Administration, Oral

KW - Diabetic Retinopathy

KW - Double-Blind Method

KW - Enzyme Inhibitors

KW - Female

KW - Humans

KW - Indoles

KW - Macular Edema

KW - Male

KW - Maleimides

KW - Middle Aged

KW - Prospective Studies

KW - Protein Kinase C

KW - Questionnaires

KW - Sickness Impact Profile

KW - Tomography, Optical Coherence

KW - Vision Disorders

KW - Visual Acuity

UR - https://www.scopus.com/pages/publications/84875430152

U2 - 10.1167/iovs.12-11055

DO - 10.1167/iovs.12-11055

M3 - Journal article

C2 - 23404115

SN - 0146-0404

VL - 54

SP - 1750

EP - 1757

JO - Investigative ophthalmology & visual science

JF - Investigative ophthalmology & visual science

IS - 3

ER -

The effect of the oral PKC β inhibitor ruboxistaurin on vision loss in two phase 3 studies

Abstract

Adgang til dokumentet

Andre filer og links

Fingeraftryk

Citationsformater