The effect of salicylazosulphapyridine (sulphasalazine) on male fertility. A review

A Giwercman, N E Skakkebaek


Salicylazosulfapyridine (SASP), a drug used in the treatment of inflammatory bowel diseases, has been reported to depress the fertility in males. Therefore, some authors have proposed SASP as a new lead in the search for a contraceptive for men. Based on a review of the literature, our conclusion is that SASP taken in tolerable doses has not sufficient antifertility effect. Additionally, the drug has too serious and too many side effects to be accepted as a contraceptive. However, the effect on male fertility of other sulfa drugs and related compounds remains to be investigated.

TidsskriftInternational Journal of Andrology
Udgave nummer1
Sider (fra-til)38-52
Antal sider15
StatusUdgivet - feb. 1986
Udgivet eksterntJa


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