The effect of phenylephrine on arterial and venous cerebral blood flow in healthy subjects

Shigehiko Ogoh, Kohei Sato, James P Fisher, Thomas Seifert, Morten Overgaard, Niels H Secher

    79 Citationer (Scopus)

    Abstract

    Sympathetic regulation of the cerebral circulation remains controversial. Although intravenous phenylephrine (PE) infusion reduces the near-infrared spectroscopy (NIRS)-determined measure of frontal lobe oxygenation (S(c) O(2) ) and increases middle cerebral artery mean blood velocity (MCA V(mean) ), suggesting α-adrenergic-mediated cerebral vasoconstriction, this remains unconfirmed by evaluation of arterial and venous cerebral blood flow.
    OriginalsprogEngelsk
    TidsskriftClinical Physiology and Functional Imaging
    Vol/bind31
    Udgave nummer6
    Sider (fra-til)445-51
    Antal sider7
    ISSN1475-0961
    DOI
    StatusUdgivet - 2011

    Fingeraftryk

    Dyk ned i forskningsemnerne om 'The effect of phenylephrine on arterial and venous cerebral blood flow in healthy subjects'. Sammen danner de et unikt fingeraftryk.

    Citationsformater