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Region Hovedstaden - en del af Københavns Universitetshospital
Udgivet

The effect of long-term treatment with coenzyme Q10 on nucleic acid modifications by oxidation in children with Down syndrome

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Vis graf over relationer

Elevated levels of oxidative nucleic acid modifications have been proposed to be associated with some of the clinical characteristics of Down syndrome. Oral intake of coenzyme Q10 improves oxidative status and shows a tendency toward protective effect on DNA oxidation in certain age groups of children with Down syndrome. Here, we demonstrate that long-term (i.e., 4 years) treatment with coenzyme Q10 (ubiquinone) at the dosage of 4 mg/kg/d does not affect whole body DNA and RNA oxidation.

OriginalsprogEngelsk
TidsskriftNeurobiology of Aging
Vol/bind67
Sider (fra-til)159-161
Antal sider3
ISSN0197-4580
DOI
StatusUdgivet - jul. 2018

ID: 53711178