The effect of elevated body mass index on ischemic heart disease risk: causal estimates from a Mendelian randomisation approach

Børge G Nordestgaard, Tom M Palmer, Marianne Benn, Jeppe Zacho, Anne Tybjaerg-Hansen, George Davey Smith, Nicholas J Timpson

235 Citationer (Scopus)

Abstract

Adiposity, assessed as elevated body mass index (BMI), is associated with increased risk of ischemic heart disease (IHD); however, whether this is causal is unknown. We tested the hypothesis that positive observational associations between BMI and IHD are causal.
OriginalsprogEngelsk
TidsskriftPLOS Medicine
Vol/bind9
Udgave nummer5
Sider (fra-til)e1001212
ISSN1549-1676
DOI
StatusUdgivet - 2012

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