The effect of antibiotic- and hydrocortisone-containing ointments in preventing secondary infections in guinea worm disease

P. Magnussen*, A. Yakubu, P. Bloch

*Corresponding author af dette arbejde
    8 Citationer (Scopus)

    Abstract

    A randomized, single-blind, controlled study comparing the efficacy of an ointment containing two antibiotics, one containing one antibiotic plus hydrocortisone, and no treatment in reducing secondary infections in patients with patent Guinea worm was undertaken in the northern region of Ghana. Seventy seven patients were included. Time to complete healing was significantly shorter in the treatment groups compared with the controls (P = 0.044 and P = 0.003, respectively). Secondary infections occurred more often in the controls (P = 0.00014). Ointments containing antibiotics are recommended for application at the early stage of patent Guinea worm infection.

    OriginalsprogEngelsk
    TidsskriftAmerican Journal of Tropical Medicine and Hygiene
    Vol/bind51
    Udgave nummer6
    Sider (fra-til)797-799
    Antal sider3
    ISSN0002-9637
    StatusUdgivet - 1994

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